HPRT1 and ISCU

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HPRT1	ISCU
Gene Name		hypoxanthine phosphoribosyltransferase 1	iron-sulfur cluster assembly enzyme
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity Guanine Phosphoribosyltransferase Activity	Iron Ion Binding Protein Binding Protein Complex Scaffold Iron-sulfur Cluster Binding
	Biological Process	Response To Amphetamine Purine Nucleobase Metabolic Process Purine Nucleotide Biosynthetic Process Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage Grooming Behavior Locomotory Behavior Cytolysis Striatum Development Cerebral Cortex Neuron Differentiation Central Nervous System Neuron Development GMP Salvage IMP Salvage Dopamine Metabolic Process Purine-containing Compound Salvage Hypoxanthine Salvage Small Molecule Metabolic Process Positive Regulation Of Dopamine Metabolic Process GMP Catabolic Process IMP Metabolic Process Hypoxanthine Metabolic Process Lymphocyte Proliferation Dendrite Morphogenesis Protein Homotetramerization Nucleobase-containing Small Molecule Metabolic Process	Nitrogen Fixation Iron-sulfur Cluster Assembly Small Molecule Metabolic Process
Pathways		Purine metabolism Metabolism of nucleotides Purine salvage
Drugs		Azathioprine Mercaptopurine Alpha-Phosphoribosylpyrophosphoric Acid Pyrophosphate 2- 5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine 3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol 9-Deazaguanine
Diseases
GWAS
Protein-Protein Interactions		5 interactors: FANCA ISCU PRTFDC1 SDCBP WDYHV1	12 interactors: AGTRAP BANP CCDC172 FAM9B GOLGA2 HPRT1 IKZF1 KRT40 LNX1 MID2 NECAB2 NUP62
Entrez ID		3251	23479
HPRD ID		02388	14828
Ensembl ID		ENSG00000165704	ENSG00000136003
Uniprot IDs		P00492	B3KQ30 B4DNC9 Q9H1K1
PDB IDs		1BZY 1D6N 1HMP 1Z7G 2VFA 3GEP 3GGC 3GGJ 4IJQ 4KN6
Enriched GO Terms of Interacting Partners?		Nitrogen Fixation Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Substrate-dependent Cell Migration, Cell Extension Cellular Component Assembly	Positive Regulation Of Neutrophil Differentiation GMP Salvage GMP Catabolic Process Guanine Salvage Cell Cycle Adenine Salvage Hypoxanthine Salvage Positive Regulation Of Dopamine Metabolic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling GMP Biosynthetic Process Purine Nucleoside Monophosphate Catabolic Process Purine Ribonucleoside Salvage Positive Regulation Of NK T Cell Differentiation Angiotensin-activated Signaling Pathway Protein Localization To Microtubule Regulation Of I-kappaB Kinase/NF-kappaB Signaling GMP Metabolic Process Positive Regulation Of Granulocyte Differentiation Protein Homooligomerization Purine Ribonucleoside Catabolic Process IMP Salvage Purine Nucleobase Biosynthetic Process Negative Regulation Of Viral Release From Host Cell Purine Nucleotide Salvage Striatum Development Negative Regulation Of Viral Entry Into Host Cell Lymph Node Development Peyer's Patch Development Regulation Of Dopamine Metabolic Process Grooming Behavior Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway IMP Biosynthetic Process Regulation Of Viral Entry Into Host Cell Natural Killer Cell Differentiation Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell Lymphocyte Activation IMP Metabolic Process Subpallium Development Positive Regulation Of ERBB Signaling Pathway Purine Ribonucleotide Catabolic Process Cytolysis Purine-containing Compound Salvage Protein Oligomerization
Tagcloud ?		cloning eif2 eif3 exerts gels gtp hershey homologue migrates migrating multisubunit p110 p116 p170 p35 p40 p44 p47 p48 p66 polyacrylamide raised recognizes ribosome sds stabilizes ternary trna
Tagcloud (Difference) ?		cloning eif2 eif3 exerts gels gtp hershey homologue migrates migrating multisubunit p110 p116 p170 p35 p40 p44 p47 p48 p66 polyacrylamide raised recognizes ribosome sds stabilizes ternary trna
Tagcloud (Intersection) ?