POLR3D and POLR3E

Number of citations of the paper that reports this interaction (PubMedID 12391170)
66

Data Source:
HPRD (in vivo)

		POLR3D	POLR3E
Description		RNA polymerase III subunit D	RNA polymerase III subunit E
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GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	DNA Binding Chromatin Binding
	Biological Process	Immune System Process Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production TRNA Transcription By RNA Polymerase III Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Immune System Process DNA-templated Transcription Innate Immune Response Defense Response To Virus
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)	Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 31562340) L-selectin levels ( 25576479)
Interacting Genes		15 interacting genes: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 KLHL20 MAPK11 MSX2 NR2E3 OGT POLR3E RBFOX2 RHOXF2 TAB1 ZNF496	2 interacting genes: POLR3A POLR3D
Entrez ID		661	55718
HPRD ID		01755	15155
Ensembl ID		ENSG00000168495	ENSG00000058600
Uniprot IDs		P05423	A0A0C4DH01 Q9NVU0
PDB IDs		7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	7A6H 7AE1 7AE3 7AEA 7AST 7ASU 7ASV 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Sequence-specific Double-stranded DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Nucleus Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Metabolic Process DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Proximal/distal Pattern Formation Anterior/posterior Pattern Specification Nucleoplasm Regulation Of Primary Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Pyroptotic Inflammatory Response Phosphodiesterase Activity, Acting On 3'-phosphoglycolate-terminated DNA Strands Class II DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Maintenance Via Base-excision Repair Positive Regulation Of TRAIL-activated Apoptotic Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Type II Interferon Binding Intracellular Receptor Signaling Pathway Transcription Regulator Complex DNA-(abasic Site) Binding Double-stranded DNA Exodeoxyribonuclease Activity Deoxyribonuclease (pyrimidine Dimer) Activity CHOP-ATF3 Complex Regionalization Protein K33-linked Ubiquitination Steroid Hormone Receptor Signaling Pathway	TRNA Transcription By RNA Polymerase III TRNA Transcription RNA Polymerase III Complex Transcription By RNA Polymerase III DNA-directed RNA Polymerase Complex Positive Regulation Of Interferon-beta Production Regulation Of Interferon-beta Production Positive Regulation Of Type I Interferon Production Regulation Of Type I Interferon Production TRNA Metabolic Process Defense Response To Virus Response To Virus DNA-templated Transcription DNA/RNA Hybrid Binding Positive Regulation Of Cytokine Production Chromatin Binding 5'-3' RNA Polymerase Activity Innate Immune Response Defense Response To Other Organism Defense Response To Symbiont Regulation Of Cytokine Production Nucleobase-containing Compound Biosynthetic Process DNA-directed RNA Polymerase Activity Response To Other Organism Immune Response Positive Regulation Of Gene Expression Response To External Biotic Stimulus Defense Response RNA Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Nucleotidyltransferase Activity Immune System Process Nucleic Acid Metabolic Process DNA Binding Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Magnesium Ion Binding
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