HOXA13 and MEIS2

Number of citations of the paper that reports this interaction (PMID 15617687)
15

Data Source:
HPRD (two hybrid)

		HOXA13	MEIS2
Gene Name		homeobox A13	Meis homeobox 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton	Nucleus
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding
	Biological Process	Skeletal System Development Vasculogenesis Endothelial Cell Morphogenesis Tissue Homeostasis Ventricular Septum Development Transcription, DNA-templated Regulation Of BMP Signaling Pathway Male Genitalia Development Embryonic Forelimb Morphogenesis Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription From RNA Polymerase II Promoter Inner Ear Development Artery Morphogenesis Branching Involved In Prostate Gland Morphogenesis Endothelial Cell Fate Specification Positive Regulation Of Mesenchymal Cell Apoptotic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Development Transcription From RNA Polymerase II Promoter Response To Mechanical Stimulus Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Growth Factor
Pathways
Drugs
Diseases
GWAS			Hyperactive-impulsive symptoms ( 18821565) Response to antipsychotic treatment ( 20195266)
Protein-Protein Interactions		6 interactors: MEIS1 MEIS2 MEIS3 SMAD1 SMAD2 SMAD5	14 interactors: ANXA1 APP ARNT2 C1orf94 CRBN DGCR6 HOXA13 HOXA9 LINC00238 OSGIN1 PBX1 SQSTM1 TRIM25 ZNHIT3
Entrez ID		3209	4212
HPRD ID		00847	03443
Ensembl ID			ENSG00000134138
Uniprot IDs		P31271 Q6DI00	B3KPD8 B7Z6F6 O14770
PDB IDs		2L7Z	3K2A
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Osteoblast Fate Commitment Primary MiRNA Processing Embryonic Pattern Specification Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development SMAD Protein Complex Assembly Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal System Development Kidney Epithelium Development Response To Growth Factor RNA Metabolic Process Regulation Of Cell Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cellular Response To BMP Stimulus Positive Regulation Of Metabolic Process Gene Expression Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Bone Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Gene Silencing By MiRNA Cell Fate Commitment Cellular Response To DsRNA Regulation Of Transcription, DNA-templated Kidney Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Posttranscriptional Gene Silencing Regulation Of RNA Metabolic Process Renal System Development Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Urogenital System Development	Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Biosynthetic Process Embryonic Limb Morphogenesis Regulation Of Cell Cycle Process Gland Development Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Limb Development Response To Estrogen Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Death Regulation Of G2/M Transition Of Mitotic Cell Cycle Developmental Process Regulation Of Cell Cycle G2/M Phase Transition Proximal/distal Pattern Formation Organ Development Regulation Of Transcription, DNA-templated Embryonic Forelimb Morphogenesis Positive Regulation Of Transcription, DNA-templated Reproductive Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Immune System Process Developmental Process Involved In Reproduction Regulation Of RNA Metabolic Process Forelimb Morphogenesis Sex Differentiation Regulation Of Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Neutrophil Clearance Prostate Gland Development Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of Cell Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Urogenital System Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Neutrophil Apoptotic Process Synaptic Growth At Neuromuscular Junction
Tagcloud ?		a2 anxa2 cancerous carcinogenesis coexpression cohorts cox curve dismutase employed escc esophageal hazards homeobox ihc kaplanmeier positively predictors predicts proportional qpcr shorter sixth sod2 squamous superoxide tnm validation	accumulative aldehyde aldh1a1 blots cbfb cxcl6 devastating diras diras3 feel glaucoma homeobox identifiable immunocytochemistry meshwork negatives pitx2 protocols pursued ranking samd5 sirnas statistic sterile subtle tm tms vis
Tagcloud (Difference) ?		a2 anxa2 cancerous carcinogenesis coexpression cohorts cox curve dismutase employed escc esophageal hazards ihc kaplanmeier positively predictors predicts proportional qpcr shorter sixth sod2 squamous superoxide tnm validation	accumulative aldehyde aldh1a1 blots cbfb cxcl6 devastating diras diras3 feel glaucoma identifiable immunocytochemistry meshwork negatives pitx2 protocols pursued ranking samd5 sirnas statistic sterile subtle tm tms vis
Tagcloud (Intersection) ?		homeobox