HOXA13 and MEIS3

Number of citations of the paper that reports this interaction (PubMedID 15617687)
0

Data Source:
HPRD (two hybrid)

		HOXA13	MEIS3
Description		homeobox A13	Meis homeobox 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Intermediate Filament Cytoskeleton	Chromatin Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Skeletal System Development Vasculogenesis Endothelial Cell Morphogenesis Tissue Homeostasis Ventricular Septum Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Animal Organ Morphogenesis Regulation Of BMP Signaling Pathway Male Genitalia Development Prostate Gland Development Response To Testosterone Embryonic Forelimb Morphogenesis Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Embryonic Hindgut Morphogenesis Inner Ear Development Artery Morphogenesis Branching Involved In Prostate Gland Morphogenesis Endothelial Cell Fate Specification Mesenchymal Cell Apoptotic Process Mitotic Nuclear Division Positive Regulation Of Mesenchymal Cell Apoptotic Process	Angiogenesis Eye Development Regulation Of DNA-templated Transcription Brain Development Positive Regulation Of Cell Population Proliferation Embryonic Pattern Specification Animal Organ Morphogenesis Hemopoiesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Hand-foot-genital syndrome Guttmacher syndrome
GWAS		Hepatitis B surface antigen seroclearance in chronic hepatitis B infection ( 29975729) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: MEIS1 MEIS2 MEIS3 SMAD1 SMAD2 SMAD5	22 interacting genes: ATXN1L CCDC116 ENKD1 FAM110A FAM110B FAM161B FAM90A1 HGS HOXA13 INTS4 LENG1 LMO3 MBD3 PIP4K2A PRPF31 PSORS1C2 SUOX TCL1B TLE5 TSGA10IP VEZF1 ZNF417
Entrez ID		3209	56917
HPRD ID		00847	14386
Ensembl ID		ENSG00000106031	ENSG00000105419
Uniprot IDs		P31271 Q6DI00	H0YNA8 H3BLU4 Q49A38 Q99687
PDB IDs		2L7Z
Enriched GO Terms of Interacting Partners?		Embryonic Pattern Specification Pattern Specification Process SMAD Protein Complex Heteromeric SMAD Protein Complex I-SMAD Binding SMAD Protein Signal Transduction Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Homomeric SMAD Protein Complex Positive Regulation Of Transcription By RNA Polymerase II Ureteric Bud Development Osteoblast Fate Commitment Animal Organ Development Anatomical Structure Morphogenesis Mesonephric Tubule Development Mesonephric Epithelium Development Transcription Regulator Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Anti-Mullerian Hormone Receptor Signaling Pathway Kidney Epithelium Development Positive Regulation Of RNA Metabolic Process Response To Growth Factor Positive Regulation Of Nucleobase-containing Compound Metabolic Process DEAD/H-box RNA Helicase Binding DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transforming Growth Factor Beta Receptor Signaling Pathway Co-SMAD Binding Sequence-specific DNA Binding Eye Development Primary MiRNA Processing Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Conduction System Development Animal Organ Morphogenesis Positive Regulation Of Biosynthetic Process Sensory Organ Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Fate Commitment Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Differentiation Pancreas Development Negative Regulation Of Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Tube Development Epithelium Development
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