HOXA13

Name	homeobox A13
Structure
Interactors	6 interactors: MEIS1 MEIS2 MEIS3 SMAD1 SMAD2 SMAD5
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Intermediate Filament Cytoskeleton
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Skeletal System Development Vasculogenesis Endothelial Cell Morphogenesis Tissue Homeostasis Ventricular Septum Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Animal Organ Morphogenesis Regulation Of BMP Signaling Pathway Male Genitalia Development Prostate Gland Development Response To Testosterone Embryonic Forelimb Morphogenesis Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Embryonic Hindgut Morphogenesis Inner Ear Development Artery Morphogenesis Branching Involved In Prostate Gland Morphogenesis Endothelial Cell Fate Specification Mesenchymal Cell Apoptotic Process Mitotic Nuclear Division Positive Regulation Of Mesenchymal Cell Apoptotic Process
Diseases	Hand-foot-genital syndrome Guttmacher syndrome
GWAS	Hepatitis B surface antigen seroclearance in chronic hepatitis B infection ( 29975729 ) Metabolite levels ( 23823483 )
Entrez ID	3209
HPRD ID	00847
Ensembl ID	ENSG00000106031
Uniprot IDs	P31271 Q6DI00
PDB IDs	2L7Z
GO Terms Enriched among Interactors ?	Embryonic Pattern Specification Pattern Specification Process SMAD Protein Complex Heteromeric SMAD Protein Complex I-SMAD Binding SMAD Protein Signal Transduction Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Homomeric SMAD Protein Complex Positive Regulation Of Transcription By RNA Polymerase II Ureteric Bud Development Osteoblast Fate Commitment Animal Organ Development Anatomical Structure Morphogenesis Mesonephric Tubule Development Mesonephric Epithelium Development Transcription Regulator Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Anti-Mullerian Hormone Receptor Signaling Pathway Kidney Epithelium Development Positive Regulation Of RNA Metabolic Process Response To Growth Factor Positive Regulation Of Nucleobase-containing Compound Metabolic Process DEAD/H-box RNA Helicase Binding DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transforming Growth Factor Beta Receptor Signaling Pathway Co-SMAD Binding Sequence-specific DNA Binding Eye Development Primary MiRNA Processing Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Conduction System Development Animal Organ Morphogenesis Positive Regulation Of Biosynthetic Process Sensory Organ Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Fate Commitment Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Differentiation Pancreas Development Negative Regulation Of Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Tube Development Epithelium Development