HNRNPH2 and DDX5

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		HNRNPH2	DDX5
Gene Name		heterogeneous nuclear ribonucleoprotein H2 (H)	DEAD (Asp-Glu-Ala-Asp) box helicase 5
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Poly(A) RNA Binding	Transcription Coactivator Activity RNA Helicase Activity ATP-dependent RNA Helicase Activity Protein Binding Calmodulin Binding ATP Binding Enzyme Binding Estrogen Receptor Binding Pre-mRNA Binding Poly(A) RNA Binding Calcium-dependent Protein Binding Androgen Receptor Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development Transcription, DNA-templated Circadian Rhythm Cell Growth Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Androgen Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: DDX5 GNB2L1 HNRNPA0 HNRNPUL1 ILF3 MSI2 PQBP1 PRMT6 PRPF31 PRPF8 QKI RAD21 RBFOX2 RBM10 RBM39 RBM4 SF1 SNRPC TEKT1 WDR83	34 interactors: AKAP8 CALM1 CREBBP DDX17 DHX9 EP300 ESR1 ESR2 FBL HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 TNNT1 TP53 WBP11
Entrez ID		3188	1655
HPRD ID		03022	01615
Ensembl ID		ENSG00000126945	ENSG00000108654
Uniprot IDs		P55795	J3KTA4 P17844
PDB IDs		1WEZ 1WG5	3FE2 4A4D
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Biogenesis Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Posttranscriptional Regulation Of Gene Expression Spliceosomal Tri-snRNP Complex Assembly Cellular Metabolic Process Negative Regulation Of Translation Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Translation Rhythmic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Metabolic Process MRNA Splice Site Selection Negative Regulation Of Cellular Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Regulation Of RNA Stability Regulation Of Metabolic Process Regulation Of Viral Genome Replication Spliceosomal Complex Assembly Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Histone H3-R2 Methylation 3'-UTR-mediated MRNA Destabilization Positive Regulation Of CAMP Catabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription	Gene Expression RNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing MRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Signal Transduction Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Signaling Response To Organic Substance Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Cell Communication Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Immune System Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Chromatin Organization Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Response To Stimulus Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Vagina Development Histone Modification Transcription, DNA-templated
Tagcloud ?			cct5 cd68 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Difference) ?			cct5 cd68 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Intersection) ?