DDX5 and DDX17

Number of citations of the paper that reports this interaction (PMID 10837141)
15

Data Source:
HPRD (two hybrid, in vivo)

		DDX5	DDX17
Gene Name		DEAD (Asp-Glu-Ala-Asp) box helicase 5	DEAD (Asp-Glu-Ala-Asp) box helicase 17
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Membrane
	Molecular Function	Transcription Coactivator Activity RNA Helicase Activity ATP-dependent RNA Helicase Activity Protein Binding Calmodulin Binding ATP Binding Enzyme Binding Estrogen Receptor Binding Pre-mRNA Binding Poly(A) RNA Binding Calcium-dependent Protein Binding Androgen Receptor Binding	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity Estrogen Receptor Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development Transcription, DNA-templated Circadian Rhythm Cell Growth Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Androgen Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Skeletal Muscle Cell Differentiation	Transcription, DNA-templated RNA Processing Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Skeletal Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: AKAP8 CALM1 CREBBP DDX17 DHX9 EP300 ESR1 ESR2 FBL HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 TNNT1 TP53 WBP11	28 interactors: APBB1 APP BYSL CREBBP CSNK2A1 DDX5 ESR2 FBL GRB2 HDAC1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 RBM15 RBM4 SF1 SF3B4 SNRNP70 SORBS3 SRA1 SREK1 U2AF2 WBP11 YWHAG
Entrez ID		1655	10521
HPRD ID		01615	10532
Ensembl ID		ENSG00000108654	ENSG00000100201
Uniprot IDs		J3KTA4 P17844	Q59F66 Q92841
PDB IDs		3FE2 4A4D
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing MRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Signal Transduction Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Signaling Response To Organic Substance Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Cell Communication Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Immune System Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Chromatin Organization Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Response To Stimulus Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Vagina Development Histone Modification Transcription, DNA-templated	RNA Metabolic Process MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing Gene Expression Nucleobase-containing Compound Metabolic Process Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Regulation Of Receptor Activity Histone Modification Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Acetylation Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway Labyrinthine Layer Morphogenesis Developmental Process Cellular Response To Hormone Stimulus Regulation Of Signal Transduction Chromatin Modification Embryonic Placenta Morphogenesis Transcription From RNA Polymerase II Promoter
Tagcloud ?		cct5 cd68 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars	34a 3a adding auf1 contexts cpeb4 dimension doxorubicin focusing hnrnpd indirect keeps master mcf7 modulated nutlin polysomal preferentially searched srsf1 subpolysomal tardbp transcriptome translational translatome uncoupled uncoupling variations ybx1
Tagcloud (Difference) ?		cct5 cd68 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars	34a 3a adding auf1 contexts cpeb4 dimension doxorubicin focusing hnrnpd indirect keeps master mcf7 modulated nutlin polysomal preferentially searched srsf1 subpolysomal tardbp transcriptome translational translatome uncoupled uncoupling variations ybx1
Tagcloud (Intersection) ?