DDX5 and WBP11

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		DDX5	WBP11
Gene Name		DEAD (Asp-Glu-Ala-Asp) box helicase 5	WW domain binding protein 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Transcription Coactivator Activity RNA Helicase Activity ATP-dependent RNA Helicase Activity Protein Binding Calmodulin Binding ATP Binding Enzyme Binding Estrogen Receptor Binding Pre-mRNA Binding Poly(A) RNA Binding Calcium-dependent Protein Binding Androgen Receptor Binding	Single-stranded DNA Binding Protein Binding Protein Phosphatase Type 1 Regulator Activity Poly(A) RNA Binding WW Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development Transcription, DNA-templated Circadian Rhythm Cell Growth Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Androgen Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Skeletal Muscle Cell Differentiation	RRNA Processing MRNA Processing RNA Splicing Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: AKAP8 CALM1 CREBBP DDX17 DHX9 EP300 ESR1 ESR2 FBL HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 TNNT1 TP53 WBP11	28 interactors: APBB1 ARF1 C5orf22 CD2BP2 CTNNBL1 DDX17 DDX5 FYN GIGYF2 GRB2 ITSN1 MCRS1 NCK2 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRPF40A RBM5 RTN4IP1 RUNX1T1 SRC TESC TRAF4 TRIP10 VIM WBP4
Entrez ID		1655	51729
HPRD ID		01615	18293
Ensembl ID		ENSG00000108654	ENSG00000084463
Uniprot IDs		J3KTA4 P17844	F5H721 Q9Y2W2
PDB IDs		3FE2 4A4D
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing MRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Signal Transduction Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Signaling Response To Organic Substance Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Cell Communication Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Immune System Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Chromatin Organization Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Response To Stimulus Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Vagina Development Histone Modification Transcription, DNA-templated	Enzyme Linked Receptor Protein Signaling Pathway RNA Splicing Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus RNA Processing MRNA Splicing, Via Spliceosome Response To Growth Factor RNA Splicing, Via Transesterification Reactions MRNA Processing Positive Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Cell Death Death Entrainment Of Circadian Clock By Photoperiod MRNA Metabolic Process T Cell Costimulation Triglyceride Catabolic Process Regulation Of Gene Expression Regulation Of Intracellular Estrogen Receptor Signaling Pathway Photoperiodism Entrainment Of Circadian Clock Regulation Of Signal Transduction Regulation Of Cellular Process Acylglycerol Catabolic Process Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Axon Guidance Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Ephrin Receptor Signaling Pathway Neurotrophin Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organismal Development Positive Regulation Of Cell-cell Adhesion Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway System Development Response To Radiation Developmental Process Anatomical Structure Development Response To Abiotic Stimulus Regulation Of Apoptotic Process Regulation Of T Cell Activation Positive Regulation Of Cell Activation Neuron Differentiation
Tagcloud ?		cct5 cd68 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Difference) ?		cct5 cd68 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Intersection) ?