HLA-DRB3 and CTAG1B

Number of citations of the paper that reports this interaction (PubMedID 11782380)
0

Data Source:
HPRD (in vitro)

		HLA-DRB3	CTAG1B
Description		major histocompatibility complex, class II, DR beta 3	cancer/testis antigen 1B
Image
GO Annotations	Cellular Component	Golgi Membrane Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Lumenal Side Of Endoplasmic Reticulum Membrane Autolysosome Membrane	Cytoplasm
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding MHC Class II Receptor Activity Peptide Antigen Binding	Protein Binding Identical Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Myeloid Dendritic Cell Antigen Processing And Presentation Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Immune Response Signal Transduction Antigen Processing And Presentation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Immune Response T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation	TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation Co-inhibition by PD-1 Interferon gamma signaling
Drugs		1D09C3 Coccidioides immitis spherule
Diseases
GWAS		Plantar warts ( 28928442)
Interacting Genes		4 interacting genes: CDCA8 CTAG1B MAP3K13 POMC	81 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1A CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MAGEC1 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX
Entrez ID		3125	1485
HPRD ID		09985	02151
Ensembl ID			ENSG00000184033
Uniprot IDs		A0A4D6G1L1 P79483	P78358
PDB IDs		2Q6W 3C5J 4H1L	1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1
Enriched GO Terms of Interacting Partners?		Cellular Pigmentation Type 1 Melanocortin Receptor Binding Positive Regulation Of Neutrophil Mediated Killing Of Fungus Type 4 Melanocortin Receptor Binding Positive Regulation Of Killing Of Cells Of Another Organism Positive Regulation Of Oxytocin Production Type 3 Melanocortin Receptor Binding Response To Melanocyte-stimulating Hormone Positive Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Neuron Maturation IkappaB Kinase Complex Binding Regulation Of Corticosterone Secretion Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity Regulation Of Branching Morphogenesis Of A Nerve Chromosome Passenger Complex Positive Regulation Of Neuron Projection Arborization Positive Regulation Of Cell Maturation Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Neuron Maturation Mitotic Spindle Midzone Assembly Spindle Midzone Assembly Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Chromocenter Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Cytokinesis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Cytokinesis Regulation Of Neuron Projection Arborization Positive Regulation Of Cell Cycle Checkpoint TRNA Threonylcarbamoyladenosine Metabolic Process Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway MAP Kinase Kinase Kinase Activity Regulation Of Cell Maturation Stress-activated MAPK Cascade Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Regulation Of Appetite Stress-activated Protein Kinase Signaling Cascade Spindle Midzone Positive Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Separation	Protein Binding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Positive Regulation Of ERAD Pathway Antigen Processing And Presentation Of Exogenous Antigen Regulation Of ERAD Pathway MHC Class II Protein Complex Binding ER To Golgi Transport Vesicle Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Peptide Antigen Binding TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Myeloid Dendritic Cell Antigen Processing And Presentation Transport Vesicle Membrane Antigen Processing And Presentation Trans-Golgi Network Membrane Skeletal Muscle Atrophy Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To ER Regulation Of Protein Ubiquitination Skeletal Muscle Adaptation Striated Muscle Atrophy Lysosomal Membrane Endocytic Vesicle Membrane Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Autolysosome Membrane Muscle Atrophy Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell MHC Class II Receptor Activity Polyubiquitin Modification-dependent Protein Binding Late Endosome Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Post-translational Protein Modification
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