| Name |
major histocompatibility complex, class II, DP alpha 1 |
major histocompatibility complex, class II, DP beta 1 |
| Structure |
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| Diseases |
|
|
| GWAS |
- Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359
)
- Allergic disease (asthma, hay fever or eczema) ( 29083406
)
- Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757
)
- Asthma ( 31619474
30929738
)
- Asthma (childhood onset) ( 30929738
)
- Autism spectrum disorder or schizophrenia ( 28540026
)
- Chronic hepatitis B infection ( 25802187
)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098
)
- Eosinophil count ( 32888494
)
- Eosinophil percentage of granulocytes ( 27863252
)
- Eosinophil percentage of white cells ( 32888494
27863252
)
- Hepatitis B ( 21750111
)
- Hepatitis B (viral clearance) ( 22737229
)
- Hip circumference adjusted for BMI ( 34021172
)
- IgA nephropathy ( 25305756
)
- Keratinocyte cancer (MTAG) ( 31174203
)
- Lung cancer ( 28604730
)
- Lung cancer in ever smokers ( 28604730
)
- Lymphocyte percentage of white cells ( 32888494
)
- Monocyte percentage of white cells ( 32888494
)
- Mortality in sepsis ( 27639821
)
- Myositis ( 26291516
)
- Nephropathy ( 21399633
)
- Persistent hepatitis B virus infection ( 33736632
)
- Pulmonary arterial hypertension ( 30527956
)
- Response to hepatitis B vaccine ( 29534301
)
- Sjögren's syndrome ( 24097066
)
- Systemic lupus erythematosus ( 32771030
)
- Systemic sclerosis ( 21779181
)
- Takayasu arteritis ( 25604533
)
- Type 1 diabetes (age at diagnosis) ( 33179336
)
|
- Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289
)
- Alanine aminotransferase levels ( 34315874
)
- Anti-rubella virus IgG levels ( 30053915
)
- Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757
)
- Aspartate aminotransferase levels ( 34315874
)
- Aspirin exacerbated respiratory disease in asthmatics ( 23180272
)
- Asthma ( 31619474
)
- Autism spectrum disorder or schizophrenia ( 28540026
)
- Chronic hepatitis B infection ( 24940741
25802187
)
- Dermatomyositis ( 27153935
)
- EGFR mutation-positive lung adenocarcinoma ( 27501781
)
- Eosinophil percentage of granulocytes ( 27863252
)
- Eosinophil percentage of white cells ( 27863252
)
- Extranodal natural killer T-cell lymphoma (nasal type) ( 27470079
)
- Gait speed in old age ( 28077804
)
- Hepatitis B ( 33736632
21750111
19349983
)
- Hepatitis B (viral clearance) ( 22737229
)
- Hepatitis B vaccine response ( 21764829
)
- Hip circumference adjusted for BMI ( 34021172
)
- IgA nephropathy ( 25305756
)
- Monocyte count ( 32888494
27863252
)
- Myositis ( 26291516
)
- Nephropathy ( 21399633
)
- Neutrophil count ( 32888494
)
- Nodular sclerosis Hodgkin lymphoma ( 29196614
)
- Persistent hepatitis B virus infection ( 33736632
27244555
)
- Plantar warts ( 28928442
)
- Primary biliary cholangitis ( 28425483
)
- Pulmonary arterial hypertension ( 30527956
)
- Response to hepatitis B vaccine ( 29534301
31243853
)
- Rosacea symptom severity ( 29771307
)
- Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848
)
- Severe aplastic anemia ( 32004448
)
- Sjögren's syndrome ( 28076899
24097066
)
- Systemic sclerosis ( 21779181
)
- Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781
)
- Wegener's granulomatosis ( 23740775
)
- White blood cell count ( 32888494
)
- White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621
)
|
| Interacting Genes |
6 interacting genes:
CD4
CD74
CNMD
HLA-DPB1
TMEM50A
TMEM50B
|
8 interacting genes:
CD74
COPB1
HLA-DPA1
LZTS2
MEOX2
ROBO2
RTN4
TRIP6
|
| Entrez ID |
3113 |
3115 |
| HPRD ID |
00835
|
00832
|
| Ensembl ID |
ENSG00000231389
|
ENSG00000223865
|
| Uniprot IDs |
P20036
X5CKE2
|
H0Y7G7
I4EC15
P04440
|
| PDB IDs |
3LQZ
4P4K
4P4R
4P57
4P5K
4P5M
7T2A
7T2B
7T2C
7T2D
|
3LQZ
4P4K
4P4R
4P57
4P5K
4P5M
7T2A
7T2B
7T2C
7T2D
|
| GO Terms Enriched among Interactors |
|
|