ANXA4 and NMT2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		ANXA4	NMT2
Description		annexin A4	N-myristoyltransferase 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell Surface Vesicle Membrane Membrane Extracellular Matrix Cytoplasmic Vesicle Nuclear Membrane Zymogen Granule Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Host Cell
	Molecular Function	Phosphatidylserine Binding Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Identical Protein Binding Calcium-dependent Protein Binding NF-kappaB Binding Transcription Regulator Inhibitor Activity	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Peptidyl-lysine N6-myristoyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Notch Signaling Pathway Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Epithelial Cell Differentiation Negative Regulation Of Interleukin-8 Production Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction	N-terminal Peptidyl-glycine N-myristoylation Regulation Of Opsin-mediated Signaling Pathway Protein Localization To Membrane Intracellular Transport Of Virus
Pathways			Membrane binding and targetting of GAG proteins eNOS activation Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Fluocinolone acetonide Copper	Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737) Palmitoleic acid (16:1n-7) levels ( 23362303)	Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Osteoporosis-related phenotypes (MTAG) ( 32107650) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		8 interacting genes: GP2 NMT2 PADI4 POT1 RHOU SMPD1 TINF2 UCHL5	14 interacting genes: ANXA4 ANXA7 APP BCL2 BTF3 CASP3 CSNK2B PPP1CC PRKCZ RBM11 SMN1 TK1 TMED9 TP53
Entrez ID		307	9397
HPRD ID		00112	11948
Ensembl ID		ENSG00000196975	ENSG00000152465
Uniprot IDs		P09525 Q6P452	B3KT39 O60551 Q5VUC6
PDB IDs		2ZOC	4C2X 6PAU
Enriched GO Terms of Interacting Partners?		Telomere Assembly Positive Regulation Of Telomere Maintenance Shelterin Complex Nuclear Telomere Cap Complex Telomere Maintenance Positive Regulation Of Chromosome Organization Telomere Capping Regulation Of Telomere Maintenance Regulation Of DNA Strand Elongation Telomere Organization Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Component Organization Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Phosphatidylcholine Phospholipase C Activity Acid Sphingomyelin Phosphodiesterase Activity Histone H3R8 Arginine Deiminase Activity Histone H3R17 Arginine Deiminase Activity Histone H3R2 Arginine Deiminase Activity Chromosome Organization Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Negative Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Glycylpeptide N-tetradecanoyltransferase Activity N-terminal Peptidyl-glycine N-myristoylation Peptidyl-lysine N6-myristoyltransferase Activity Histone H3R26 Arginine Deiminase Activity Histone Arginine Deiminase Activity Positive Regulation Of Telomeric Loop Disassembly Perinucleolar Chromocenter Regulation Of DNA Metabolic Process Termination Of Signal Transduction 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Positive Regulation Of Organelle Organization Negative Regulation Of DNA Metabolic Process N-terminal Protein Myristoylation Telomeric D-loop Binding Protein-arginine Deiminase Activity Single-stranded Telomeric DNA Binding Regulation Of Cellular Component Organization	Response To Light Stimulus B Cell Lineage Commitment Leukocyte Apoptotic Process Glial Cell Apoptotic Process Nucleus Positive Regulation Of Neuron Apoptotic Process Response To Radiation Regulation Of Neuron Apoptotic Process Protein Tetramerization Identical Protein Binding Developmental Process Response To Metal Ion Negative Regulation Of Cell Population Proliferation Developmental Growth Molecular Function Activator Activity Positive Regulation Of Amyloid Precursor Protein Catabolic Process Protein Phosphatase 2A Binding Neuron Apoptotic Process T Cell Apoptotic Process B Cell Homeostasis Response To UV Release Of Cytochrome C From Mitochondria Response To Ionizing Radiation Protease Binding Response To Oxidative Stress Hematopoietic Stem Cell Differentiation Response To X-ray Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Neuron Maturation T Cell Lineage Commitment Positive Regulation Of Excitatory Postsynaptic Potential Vesicle Membrane Lymphocyte Apoptotic Process T Cell Homeostasis Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway Cell Fate Commitment Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of T Cell Apoptotic Process Regulation Of Glial Cell Proliferation Regulation Of Apoptotic Process Response To Nicotine T Cell Differentiation In Thymus Regulation Of Programmed Cell Death Cytoplasm Cellular Developmental Process Calcium-dependent Phospholipid Binding
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