ANXA4

Name	annexin A4
Structure
Interactors	8 interactors: GP2 NMT2 PADI4 POT1 RHOU SMPD1 TINF2 UCHL5
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell Surface Vesicle Membrane Membrane Extracellular Matrix Cytoplasmic Vesicle Nuclear Membrane Zymogen Granule Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Identical Protein Binding Calcium-dependent Protein Binding NF-kappaB Binding Transcription Regulator Inhibitor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Notch Signaling Pathway Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Epithelial Cell Differentiation Negative Regulation Of Interleukin-8 Production Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction
Drugs	Fluocinolone acetonide Copper
GWAS	Atrial fibrillation ( 28416818 30061737 ) Palmitoleic acid (16:1n-7) levels ( 23362303 )
Entrez ID	307
HPRD ID	00112
Ensembl ID	ENSG00000196975
Uniprot IDs	P09525 Q6P452
PDB IDs	2ZOC
GO Terms Enriched among Interactors ?	Telomere Assembly Positive Regulation Of Telomere Maintenance Shelterin Complex Nuclear Telomere Cap Complex Telomere Maintenance Positive Regulation Of Chromosome Organization Telomere Capping Regulation Of Telomere Maintenance Regulation Of DNA Strand Elongation Telomere Organization Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Component Organization Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Phosphatidylcholine Phospholipase C Activity Acid Sphingomyelin Phosphodiesterase Activity Histone H3R8 Arginine Deiminase Activity Histone H3R17 Arginine Deiminase Activity Histone H3R2 Arginine Deiminase Activity Chromosome Organization Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Negative Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Glycylpeptide N-tetradecanoyltransferase Activity N-terminal Peptidyl-glycine N-myristoylation Peptidyl-lysine N6-myristoyltransferase Activity Histone H3R26 Arginine Deiminase Activity Histone Arginine Deiminase Activity Positive Regulation Of Telomeric Loop Disassembly Perinucleolar Chromocenter Regulation Of DNA Metabolic Process Termination Of Signal Transduction 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Positive Regulation Of Organelle Organization Negative Regulation Of DNA Metabolic Process N-terminal Protein Myristoylation Telomeric D-loop Binding Protein-arginine Deiminase Activity Single-stranded Telomeric DNA Binding Regulation Of Cellular Component Organization