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HDLBP and DHX9
Number of citations of the paper that reports this interaction (PMID
15723802
)
27
Data Source:
HPRD
(in vitro)
HDLBP
DHX9
Gene Name
high density lipoprotein binding protein
DEAH (Asp-Glu-Ala-His) box helicase 9
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
High-density Lipoprotein Particle
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
Cytosol
Membrane
Ribonucleoprotein Complex
Cytoplasmic Ribonucleoprotein Granule
CRD-mediated MRNA Stability Complex
Molecular Function
Protein Binding
Lipid Binding
Poly(A) RNA Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
RNA Helicase Activity
ATP-dependent DNA Helicase Activity
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Biological Process
Lipid Transport
Cholesterol Metabolic Process
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
RNA Processing
Circadian Rhythm
RNA Splicing
Gene Expression
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Cellular Response To Heat
Innate Immune Response
CRD-mediated MRNA Stabilization
Pathways
mRNA Splicing
Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll Like Receptor TLR6:TLR2 Cascade
RIP-mediated NFkB activation via ZBP1
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
ZBP1(DAI) mediated induction of type I IFNs
MyD88 dependent cascade initiated on endosome
MyD88:Mal cascade initiated on plasma membrane
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Toll Like Receptor 9 (TLR9) Cascade
Innate Immune System
Processing of Capped Intron-Containing Pre-mRNA
TRIF-mediated TLR3/TLR4 signaling
Cytosolic sensors of pathogen-associated DNA
mRNA Splicing - Major Pathway
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Toll-Like Receptors Cascades
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
TRAF6 mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
7 interactors:
ADAR
CSNK2A1
DHX9
FAM46A
SMAD4
SOS1
XPOT
40 interactors:
ACTA1
AKAP8L
APBB1
BRCA1
DDX20
DDX5
EIF2AK2
EWSR1
GEMIN2
GEMIN4
GTF2B
H2AFX
HDLBP
HNRNPC
HNRNPK
IL7R
ILF3
JUN
KHDRBS1
MBD2
MGEA5
NXF1
PCNA
POLR2A
PRMT1
PRPF40A
PRPF8
RBM4
RELA
SMN1
SMN2
SNRPB
SNRPB2
SRPK1
SSRP1
STAU1
TBP
TOP2A
UBE2I
YWHAQ
Entrez ID
3069
1660
HPRD ID
00813
04386
Ensembl ID
ENSG00000115677
ENSG00000135829
Uniprot IDs
Q00341
B3KU66
Q08211
PDB IDs
1VIG
1VIH
2CTE
2CTF
2CTJ
2CTK
2CTL
2CTM
3LLM
3VYX
3VYY
Enriched GO Terms of Interacting Partners
?
Axon Guidance
Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Negative Regulation Of Protein Catabolic Process
Chemotaxis
Nuclear Export
Regulation Of Cell Death
Negative Regulation Of RNA Interference
TRNA Export From Nucleus
Nephrogenic Mesenchyme Morphogenesis
Neuron Projection Morphogenesis
Osteoblast Differentiation
Adenosine To Inosine Editing
Nephrogenic Mesenchyme Development
Metanephric Mesenchyme Morphogenesis
Cell Morphogenesis Involved In Differentiation
Cell Differentiation
Response To External Stimulus
Innate Immune Response
Neuron Projection Development
Cell Projection Morphogenesis
CRD-mediated MRNA Stabilization
Cell Part Morphogenesis
Negative Regulation Of Protein Metabolic Process
Endocardial Cell Differentiation
Hematopoietic Stem Cell Homeostasis
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Base Conversion Or Substitution Editing
Neuron Development
Negative Regulation Of Cell Death
Negative Regulation Of Type I Interferon-mediated Signaling Pathway
Formation Of Anatomical Boundary
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Endothelial Cell Activation
Nucleocytoplasmic Transport
Nuclear Transport
Cell Morphogenesis
MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA
Regulation Of Transforming Growth Factor Beta2 Production
Ossification
Positive Regulation Of SMAD Protein Import Into Nucleus
Atrioventricular Valve Formation
Sebaceous Gland Development
Neuron Differentiation
Rhythmic Process
Cell Projection Organization
Somite Rostral/caudal Axis Specification
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
MRNA Processing
RNA Splicing
MRNA Metabolic Process
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Spliceosomal SnRNP Assembly
Nitrogen Compound Metabolic Process
Regulation Of Viral Process
Regulation Of Viral Genome Replication
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Viral Process
Positive Regulation Of DNA Metabolic Process
Regulation Of Gene Expression
Ribonucleoprotein Complex Assembly
Viral Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Cellular Macromolecular Complex Assembly
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Macromolecule Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Chromosome Organization
Positive Regulation Of Response To DNA Damage Stimulus
Negative Regulation Of Viral Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Viral Genome Replication
Tagcloud
?
accurately
adam12
cancers
candidate
centb1
centg1
dip2c
exome
gli1
grin2d
hedgehog
ikbkb
infrequent
involvement
kb
kpna5
mutation
nfkb1
notch
notch1
otof
pik3ca
point
prevalence
recurring
sequencing
somatic
strengthen
substantial
Tagcloud (Difference)
?
accurately
adam12
cancers
candidate
centb1
centg1
dip2c
exome
gli1
grin2d
hedgehog
ikbkb
infrequent
involvement
kb
kpna5
mutation
nfkb1
notch
notch1
otof
pik3ca
point
prevalence
recurring
sequencing
somatic
strengthen
substantial
Tagcloud (Intersection)
?