HDLBP

Name	high density lipoprotein binding protein
Structure
Interactors	18 interactors: ADAR CDC42 CEBPA DHX9 ERBB2 ESR1 FILNC1 HMGB1 HMGB2 HSPB1 NEIL3 PLXNB2 RNF10 SMAD4 SOS1 SUMO2 TENT5A XPOT
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane High-density Lipoprotein Particle
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Lipid Binding Cadherin Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Steroid Metabolic Process Cholesterol Metabolic Process
Pathways	HDL clearance
GWAS	Apolipoprotein A1 levels ( 32203549 ) Apolipoprotein B levels ( 32203549 ) Fibrinogen levels ( 26561523 28107422 ) HDL cholesterol levels ( 32203549 ) Intraocular pressure ( 29617998 ) Mean reticulocyte volume ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Prostate cancer ( 23535732 ) Serum alkaline phosphatase levels ( 33547301 ) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625 ) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625 ) Waist circumference adjusted for BMI in non-smokers ( 28443625 )
Entrez ID	3069
HPRD ID	00813
Ensembl ID	ENSG00000115677
Uniprot IDs	A0A024R4E5 B2R5V9 Q00341
PDB IDs	1VIG 1VIH 2CTE 2CTF 2CTJ 2CTK 2CTL 2CTM
GO Terms Enriched among Interactors ?	Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Multicellular Organismal Development Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Development Regulation Of Cell Population Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Metabolic Process Regulation Of Multicellular Organismal Process Single-stranded DNA Binding Regulation Of Developmental Process Transcription Cis-regulatory Region Binding Regulation Of Cell Differentiation Double-stranded DNA Binding Positive Regulation Of Interferon-beta Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Supercoiled DNA Binding Regulation Of Primary Metabolic Process Positive Regulation Of Cell Population Proliferation Regulation Of RNA Metabolic Process DNA Geometric Change Bubble DNA Binding Positive Regulation Of RNA Metabolic Process Regulation Of Interferon-beta Production Positive Regulation Of Viral Process Negative Regulation Of RNA Metabolic Process Damaged DNA Binding RISC Complex Assembly DNA Topological Change Positive Regulation Of Epithelial Cell Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Double-stranded RNA Binding Response To Stress RNA Binding Regulation Of Protein Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Hemopoiesis Cell Population Proliferation RAGE Receptor Binding Regulation Of Innate Immune Response Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process RNA Stabilization Protein-containing Complex