H3F3A and SS18

Number of citations of the paper that reports this interaction (PMID 11591653)
37

Data Source:
HPRD (in vivo)

		H3F3A	SS18
Gene Name		H3 histone, family 3A	synovial sarcoma translocation, chromosome 18
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Nuclear Nucleosome Extracellular Region Nucleus Nucleoplasm Protein Complex Extracellular Vesicular Exosome	Nucleus Cytoplasmic Microtubule NpBAF Complex
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Protein Binding Nucleosomal DNA Binding Protein Heterodimerization Activity	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Chromatin Silencing At RDNA DNA Replication-independent Nucleosome Assembly Blood Coagulation Gene Expression Positive Regulation Of Cell Growth DNA Methylation On Cytosine Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Microtubule Cytoskeleton Organization Cell Morphogenesis Transcription, DNA-templated Intracellular Signal Transduction Response To Drug Positive Regulation Of Transcription From RNA Polymerase II Promoter Ephrin Receptor Signaling Pathway Neuronal Stem Cell Maintenance
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Cellular Senescence Signaling by Wnt M Phase Amyloids NoRC negatively regulates rRNA expression RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression Factors involved in megakaryocyte development and platelet production PRC2 methylates histones and DNA Cell Cycle, Mitotic Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		25 interactors: ASF1A ASF1B BPTF BRD1 CABIN1 CARM1 CBX3 CHD1 CREBBP DAXX KAT2B KMT2A MAPK9 NOS3 PARP10 SETD7 SMARCA1 SMARCA4 SMARCA5 SS18 SSRP1 SUPT16H TLE2 UHRF1 ZMYND11	8 interactors: EP300 GRB2 H3F3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4
Entrez ID		3020	6760
HPRD ID		03082	02559
Ensembl ID		ENSG00000163041	ENSG00000141380
Uniprot IDs		B2R4P9 P84243	B4DLD3 B4E2J6 Q15532 Q4VAX0
PDB IDs		2L43 3ASK 3ASL 3AV2 3JVK 3MUK 3MUL 3QL9 3QLA 3QLC 4GNE 4GNF 4GNG 4GU0 4GUR 4GUS 4GY5 4H9N 4H9O 4H9P 4H9Q 4H9R 4H9S 4HGA 4L58
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Chromosome Organization Organelle Organization Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process Chromatin Remodeling Gene Expression Biosynthetic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleosome Organization Chromatin Assembly Or Disassembly Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Histone Modification Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process DNA Replication-independent Nucleosome Assembly Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Nucleosome Assembly Internal Protein Amino Acid Acetylation Peptidyl-lysine Modification Protein Acetylation Chromatin Assembly Negative Regulation Of Cellular Metabolic Process DNA Conformation Change Negative Regulation Of Biosynthetic Process Protein-DNA Complex Assembly Negative Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Viral Process	Aortic Smooth Muscle Cell Differentiation Chromatin Organization Positive Regulation By Host Of Viral Transcription DNA Methylation On Cytosine Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Vascular Smooth Muscle Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway Chromatin Modification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Interaction With Symbiont Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Chromatin Silencing Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Transcription Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Smooth Muscle Cell Differentiation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cell Growth DNA Methylation Positive Regulation Of Metabolic Process Gene Expression Histone Modification Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone H2B Acetylation Transcription, DNA-templated DNA Modification RNA Biosynthetic Process Muscle Structure Development Gene Silencing Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Internal Peptidyl-lysine Acetylation
Tagcloud ?		36me3 atrx code combinatorial commonest daxx g34r g34v gbms global h3k h3k27me3 h3k36me3 h3k4me3 h3k9me3 highlights hist1h3b idh1 innovative k27m mark marks notably opportunity pediatric polycomb tailored trimethylation underlies	5p algorithms amenable cdkn1a colonies confer conferred fuji hs innovative meanwhile mib mir miranda mirna noteworthy oncomir oncoprotein p21 pictar sarcoma sarcomas ssx succeeded suppressors syii synovial tumorigenicity utr
Tagcloud (Difference) ?		36me3 atrx code combinatorial commonest daxx g34r g34v gbms global h3k h3k27me3 h3k36me3 h3k4me3 h3k9me3 highlights hist1h3b idh1 k27m mark marks notably opportunity pediatric polycomb tailored trimethylation underlies	5p algorithms amenable cdkn1a colonies confer conferred fuji hs meanwhile mib mir miranda mirna noteworthy oncomir oncoprotein p21 pictar sarcoma sarcomas ssx succeeded suppressors syii synovial tumorigenicity utr
Tagcloud (Intersection) ?		innovative