GUCY2D and RGS9

Number of citations of the paper that reports this interaction (PMID 11485301)
2

Data Source:
HPRD (in vivo)

		GUCY2D	RGS9
Gene Name		guanylate cyclase 2D, membrane (retina-specific)	regulator of G-protein signaling 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Outer Membrane Integral Component Of Plasma Membrane Photoreceptor Disc Membrane	Nucleus Cytoplasm Heterotrimeric G-protein Complex Plasma Membrane
	Molecular Function	Guanylate Cyclase Activity Protein Kinase Activity Receptor Activity ATP Binding GTP Binding	Signal Transducer Activity GTPase Activator Activity Protein Complex Binding
	Biological Process	CGMP Biosynthetic Process Protein Phosphorylation Receptor Guanylyl Cyclase Signaling Pathway Visual Perception Phototransduction, Visible Light Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction	Dopamine Receptor Signaling Pathway Nervous System Development Visual Perception Phototransduction, Visible Light Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity Response To Estrogen
Pathways		Inactivation, recovery and regulation of the phototransduction cascade Visual phototransduction The phototransduction cascade Diseases associated with visual transduction	Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: GUCA1A GUCA1B GUCA2B RGS9 S100B	5 interactors: ADRB2 GNAT1 GNB5 GUCY2D RGS9BP
Entrez ID		3000	8787
HPRD ID		02550	04962
Ensembl ID		ENSG00000132518	ENSG00000108370
Uniprot IDs		Q02846	A8K1G1 O75916
PDB IDs		1AWL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Guanylate Cyclase Activity Positive Regulation Of CGMP Biosynthetic Process Positive Regulation Of CGMP Metabolic Process Regulation Of CGMP Biosynthetic Process Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of CGMP Metabolic Process Rhodopsin Mediated Signaling Pathway Positive Regulation Of Lyase Activity Regulation Of Cyclase Activity Phototransduction, Visible Light Positive Regulation Of Cyclic Nucleotide Metabolic Process Detection Of Visible Light Phototransduction Cellular Response To Light Stimulus Detection Of Light Stimulus Cellular Response To Radiation Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Sensory Perception Of Light Stimulus Response To Abiotic Stimulus Response To Light Stimulus Neurological System Process Response To Radiation Positive Regulation Of Catalytic Activity Detection Of Stimulus Body Fluid Secretion Sensory Perception Regulation Of Catalytic Activity Negative Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Signal Transduction G-protein Coupled Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Response To Methylmercury Receptor Guanylyl Cyclase Signaling Pathway Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Skeletal Muscle Cell Differentiation Response To Steroid Hormone Response To External Stimulus CGMP Biosynthetic Process Negative Regulation Of Skeletal Muscle Tissue Development Regulation Of Body Fluid Levels CGMP Metabolic Process Secretion Dopamine Receptor Signaling Pathway Astrocyte Differentiation Cyclic Purine Nucleotide Metabolic Process Excretion	Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Detection Of Light Stimulus Cellular Response To Radiation Detection Of Abiotic Stimulus Response To Light Stimulus Response To Abiotic Stimulus G-protein Coupled Receptor Signaling Pathway Response To Radiation Detection Of Stimulus Response To External Stimulus Detection Of Light Stimulus Involved In Visual Perception Visual Perception Sensory Perception Of Light Stimulus Regulation Of Signal Transduction Regulation Of Signaling Cell Surface Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Sensory Perception G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Signal Transduction Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Signaling Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Cell Communication Neurological System Process Negative Regulation Of Voltage-gated Calcium Channel Activity Sensory Perception Of Umami Taste Heat Generation Diet Induced Thermogenesis Cellular Response To Stimulus Receptor Guanylyl Cyclase Signaling Pathway Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Cellular Response To Electrical Stimulus Response To Light Intensity Detection Of Stimulus Involved In Sensory Perception Negative Regulation Of Smooth Muscle Contraction Adrenergic Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Response To Dietary Excess Negative Regulation Of Cation Channel Activity CGMP Biosynthetic Process
Tagcloud ?		acuities acuity advancing aipl1 amaurosis cep290 childhood corrected counseling crb1 crx departments exclusion infancy lca lca5 leber multicentered ophthalmology participating pigmentosa rdh12 retinitis rp rpe65 rpgrip1 tulp1 visit visual	0mg 5months accumulated amphetamine caloric calorimetry consumption dark dioxide expenditure factoring hour indicative indirect influences ko littermates locomotor male modulates opioid psychostimulant respective sensitization striatum utilize weights wt
Tagcloud (Difference) ?		acuities acuity advancing aipl1 amaurosis cep290 childhood corrected counseling crb1 crx departments exclusion infancy lca lca5 leber multicentered ophthalmology participating pigmentosa rdh12 retinitis rp rpe65 rpgrip1 tulp1 visit visual	0mg 5months accumulated amphetamine caloric calorimetry consumption dark dioxide expenditure factoring hour indicative indirect influences ko littermates locomotor male modulates opioid psychostimulant respective sensitization striatum utilize weights wt
Tagcloud (Intersection) ?