RGS9 and GNAT1

Number of citations of the paper that reports this interaction (PubMedID 12119397)
51

Data Source:
HPRD (in vivo)

		RGS9	GNAT1
Description		regulator of G protein signaling 9	G protein subunit alpha transducin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Presynaptic Membrane Neuron Projection Postsynaptic Density Membrane Glutamatergic Synapse	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Membrane Apical Plasma Membrane Photoreceptor Connecting Cilium Photoreceptor Outer Segment Membrane Cell Projection Neuronal Cell Body Photoreceptor Disc Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Acyl Binding Nucleotide Binding G Protein-coupled Receptor Binding GTPase Activity GTP Binding Guanyl Nucleotide Binding GDP Binding Protein Kinase Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway G Protein-coupled Dopamine Receptor Signaling Pathway Nervous System Development Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Estradiol Intracellular Signal Transduction Light Adaption Regulation Of Calcium Ion Export Across Plasma Membrane Dark Adaptation	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Phototransduction, Visible Light Visual Behavior Cell Population Proliferation Response To Light Stimulus Detection Of Light Stimulus Response To Light Intensity Dopamine Secretion G Protein-coupled Opsin Signaling Pathway Regulation Of Opsin-mediated Signaling Pathway Eye Photoreceptor Cell Development Retinal Cone Cell Differentiation Detection Of Light Stimulus Involved In Visual Perception Sensory Perception Of Umami Taste Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Retina Development In Camera-type Eye Retinal Rod Cell Differentiation Cellular Response To Electrical Stimulus Neural Tissue Regeneration Background Adaptation
Pathways		G alpha (i) signalling events G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade G alpha (i) signalling events
Drugs			Cacodylic acid Guanosine-5'-Diphosphate Tetrafluoroaluminate Ion
Diseases		Bradyopsia	Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS		Adverse response to antithyroid drugs in Graves disease ( 30067105) Heel bone mineral density ( 28869591 30598549)	Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Schizophrenia ( 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: ADRB2 DRD3 GNAT1 GNB5 GUCY2D RGS9BP	3 interacting genes: F2R RGS16 RGS9
Entrez ID		8787	2779
HPRD ID		04962	08850
Ensembl ID		ENSG00000108370	ENSG00000114349
Uniprot IDs		A8K1G1 O75916	P11488
PDB IDs			3RBQ
Enriched GO Terms of Interacting Partners?		Regulation Of G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Response To Light Stimulus Response To Radiation Photoreceptor Outer Segment Membrane Regulation Of Opsin-mediated Signaling Pathway Response To Light Intensity System Process G Protein-coupled Dopamine Receptor Signaling Pathway Visual Perception Detection Of Light Stimulus Involved In Visual Perception Sensory Perception Of Light Stimulus Photoreceptor Disc Membrane Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Heterotrimeric G-protein Complex Nervous System Process Negative Regulation Of Blood Pressure Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Metal Ion Transport Detection Of Light Stimulus Visual Behavior Photoreceptor Outer Segment Signal Transduction Regulation Of Monoatomic Ion Transport Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity GTPase Activator Complex G-protein Gamma-subunit Binding Sensory Perception Beta2-adrenergic Receptor Activity Musculoskeletal Movement, Spinal Reflex Action Acyl Binding Cellular Response To Light Stimulus Background Adaptation Dark Adaptation Detection Of Abiotic Stimulus Regulation Of Signal Transduction Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Neural Tissue Regeneration Detection Of Stimulus Involved In Sensory Perception Light Adaption Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Response To Psychosocial Stress Regulation Of Cell Communication Norepinephrine Binding Regulation Of Blood Pressure Positive Regulation Of Lipophagy	Visual Perception Sensory Perception Of Light Stimulus System Process Sensory Perception Dendritic Cell Homeostasis Negative Regulation Of Renin Secretion Into Blood Stream G Protein-coupled Receptor Signaling Pathway Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission Establishment Of Synaptic Specificity At Neuromuscular Junction Regulation Of Calcium Ion Transmembrane Transport Regulation Of G Protein-coupled Receptor Signaling Pathway Dark Adaptation Nervous System Process Platelet Dense Tubular Network Regulation Of Renin Secretion Into Blood Stream Light Adaption Negative Regulation Of Glomerular Filtration Thrombin-activated Receptor Activity Regulation Of Calcium Ion Transport Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Regulation Of Monoatomic Cation Transmembrane Transport GTPase Activator Activity Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Monoatomic Ion Transmembrane Transport GTPase Activity Connective Tissue Replacement Regulation Of Glomerular Filtration Regulation Of Metal Ion Transport Thrombin-activated Receptor Signaling Pathway Trans-synaptic Signaling, Modulating Synaptic Transmission Regulation Of Monoatomic Ion Transport Glutamate Secretion Response To Light Intensity Transcription Factor TFTC Complex Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Cell-cell Junction Maintenance G-protein Beta-subunit Binding G Protein-coupled Dopamine Receptor Signaling Pathway Positive Regulation Of Collagen Biosynthetic Process SAGA Complex Platelet Dense Granule Organization Positive Regulation Of Blood Coagulation Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Vasoconstriction Positive Regulation Of Coagulation Positive Regulation Of Smooth Muscle Contraction G-protein Alpha-subunit Binding Negative Regulation Of Microtubule Depolymerization Response To Amphetamine Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
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