RGS9 and DRD3

Number of citations of the paper that reports this interaction (PubMedID 32828283)
0

Data Source:
BioGRID (pull down)

		RGS9	DRD3
Description		regulator of G protein signaling 9	dopamine receptor D3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Presynaptic Membrane Neuron Projection Postsynaptic Density Membrane Glutamatergic Synapse	Plasma Membrane Membrane Synapse
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go G Protein-coupled Receptor Activity Dopamine Neurotransmitter Receptor Activity Protein Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway G Protein-coupled Dopamine Receptor Signaling Pathway Nervous System Development Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Estradiol Intracellular Signal Transduction Light Adaption Regulation Of Calcium Ion Export Across Plasma Membrane Dark Adaptation	Synaptic Transmission, Dopaminergic G Protein-coupled Receptor Internalization Intracellular Calcium Ion Homeostasis Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Learning Or Memory Learning Locomotory Behavior Visual Learning Response To Xenobiotic Stimulus Regulation Of Dopamine Secretion Positive Regulation Of Cytokinesis Circadian Regulation Of Gene Expression Response To Histamine Social Behavior Response To Cocaine Dopamine Metabolic Process Regulation Of Potassium Ion Transport Response To Morphine Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Blood Pressure Positive Regulation Of Mitotic Nuclear Division Acid Secretion Behavioral Response To Cocaine Negative Regulation Of Oligodendrocyte Differentiation Arachidonate Secretion Negative Regulation Of Protein Secretion Musculoskeletal Movement, Spinal Reflex Action Negative Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Amine Transport Negative Regulation Of Synaptic Transmission, Glutamatergic Prepulse Inhibition Phospholipase C-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Secretion By Cell
Pathways		G alpha (i) signalling events G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Dopamine receptors G alpha (i) signalling events
Drugs			Ziprasidone Cabergoline Ropinirole Dihydroergotamine Olanzapine Clozapine Sulpiride Loxapine Remoxipride Pramipexole Chlorpromazine Buspirone Haloperidol Amoxapine Lisuride Apomorphine Flupentixol Dopamine Ergoloid mesylate Pimozide Domperidone Pergolide Bromocriptine Quetiapine Levodopa Aripiprazole Chlorprothixene Paliperidone Yohimbine Methotrimeprazine Iloperidone Rotigotine Norclozapine Cariprazine Mianserin Asenapine Amisulpride Sarizotan Sumanirole Nandrolone decanoate Captodiame AS-8112 Blonanserin Pipamperone Tianeptine Dihydro-alpha-ergocryptine Epicriptine Pardoprunox Piribedil Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases		Bradyopsia
GWAS		Adverse response to antithyroid drugs in Graves disease ( 30067105) Heel bone mineral density ( 28869591 30598549)	Chronotype ( 30696823) Feeling hurt ( 29500382) Personality dimensions ( 23903073) Smooth-surface caries ( 24556642)
Interacting Genes		6 interacting genes: ADRB2 DRD3 GNAT1 GNB5 GUCY2D RGS9BP	16 interacting genes: CLIC6 DRD1 EEF1B2 EEF1G EPB41 EPB41L1 EPB41L2 FLNA GIPC1 GNAI1 GRB2 MPDZ NCK1 NCS1 RDX RGS9
Entrez ID		8787	1814
HPRD ID		04962	00540
Ensembl ID		ENSG00000108370	ENSG00000151577
Uniprot IDs		A8K1G1 O75916	A1A4V4 A8K8E4 E9PCM4 P35462 X5D2G4
PDB IDs			3PBL 7CMU 7CMV 8IRT 9F33 9F34
Enriched GO Terms of Interacting Partners?		Regulation Of G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Response To Light Stimulus Response To Radiation Photoreceptor Outer Segment Membrane Regulation Of Opsin-mediated Signaling Pathway Response To Light Intensity System Process G Protein-coupled Dopamine Receptor Signaling Pathway Visual Perception Detection Of Light Stimulus Involved In Visual Perception Sensory Perception Of Light Stimulus Photoreceptor Disc Membrane Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Heterotrimeric G-protein Complex Nervous System Process Negative Regulation Of Blood Pressure Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Metal Ion Transport Detection Of Light Stimulus Visual Behavior Photoreceptor Outer Segment Signal Transduction Regulation Of Monoatomic Ion Transport Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity GTPase Activator Complex G-protein Gamma-subunit Binding Sensory Perception Beta2-adrenergic Receptor Activity Musculoskeletal Movement, Spinal Reflex Action Acyl Binding Cellular Response To Light Stimulus Background Adaptation Dark Adaptation Detection Of Abiotic Stimulus Regulation Of Signal Transduction Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Neural Tissue Regeneration Detection Of Stimulus Involved In Sensory Perception Light Adaption Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Response To Psychosocial Stress Regulation Of Cell Communication Norepinephrine Binding Regulation Of Blood Pressure Positive Regulation Of Lipophagy	Cell Cortex Positive Regulation Of Protein Localization To Cell Cortex Regulation Of Protein Localization To Cell Cortex Cytoskeletal Protein Binding G Protein-coupled Dopamine Receptor Signaling Pathway Actin Binding D2 Dopamine Receptor Binding Cortical Actin Cytoskeleton Organization Positive Regulation Of Protein Localization Vesicle Membrane Presynaptic Modulation Of Chemical Synaptic Transmission Cortical Cytoskeleton Organization Regulation Of Cytoskeleton Organization Cadherin Binding Plasma Membrane Actin Cytoskeleton Organization Actin Filament-based Process Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Neuron Migration Cytoplasm Translation Elongation Factor Activity Regulation Of Actin Filament Organization Actomyosin Structure Organization Glutamatergic Synapse Regulation Of Protein Localization Negative Regulation Of Protein Catabolic Process Regulation Of Actin Filament Polymerization Spectrin Binding Cortical Cytoskeleton Ephrin Receptor Binding Positive Regulation Of Intracellular Transport Regulation Of Metal Ion Transport Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Response To Amphetamine Regulation Of Actin Filament Length Positive Regulation Of Potassium Ion Transport Regulation Of Protein Localization To Cell Periphery COP9 Signalosome Regulation Of Protein Catabolic Process Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Positive Regulation Of Supramolecular Fiber Organization Regulation Of Transport Regulation Of Monoatomic Ion Transport Extracellular Exosome Structural Molecule Activity Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Dendritic Shaft Positive Regulation Of Cytoskeleton Organization
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