ACAA1 and TXNDC11

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ACAA1	TXNDC11
Description		acetyl-CoA acyltransferase 1	thioredoxin domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Peroxisome Peroxisomal Matrix Cytosol Membrane Specific Granule Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-acyltransferase Activity Protein Binding Acetate CoA-transferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Acetyl-CoA C-myristoyltransferase Activity Long-chain Fatty Acyl-CoA Oxidase Activity	Protein Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Metabolic Process Phenylacetate Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process
Pathways		alpha-linolenic acid (ALA) metabolism Beta-oxidation of very long chain fatty acids Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Thyroxine biosynthesis
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756)	Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 24390342 30423114) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549) Weight ( 28552196)
Interacting Genes		4 interacting genes: FEM1A HAT1 TFCP2 TXNDC11	22 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 NRIP1 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417
Entrez ID		30	51061
HPRD ID		06815	07125
Ensembl ID		ENSG00000060971	ENSG00000153066
Uniprot IDs		A0A024R2M6 A0A140VJX0 P09110	Q6PKC3
PDB IDs		2IIK
Enriched GO Terms of Interacting Partners?		EP4 Subtype Prostaglandin E2 Receptor Binding	Superoxide-generating NAD(P)H Oxidase Activity Thyroid Hormone Generation Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification Thyroid Hormone Metabolic Process Cuticle Development Reactive Oxygen Species Metabolic Process Peroxidase Activity Hydrogen Peroxide Metabolic Process Cytokine-mediated Signaling Pathway Cellular Detoxification Heme Binding Hormone Biosynthetic Process Ovulation Cycle Process Superoxide Metabolic Process Hydrogen Peroxide Biosynthetic Process Scaffold Protein Binding NAD(P)H Oxidase H2O2-forming Activity Erythrocyte Differentiation Ovulation Phenol-containing Compound Metabolic Process Reactive Oxygen Species Biosynthetic Process NADPH Oxidase Complex Superoxide Anion Generation Nuclear Matrix Regulation Of Wound Healing Lipid Storage Response To Purine-containing Compound Acetate CoA-transferase Activity Phenylacetate Catabolic Process NADP Binding Modified Amino Acid Metabolic Process Iodide Peroxidase Activity Ovarian Follicle Rupture Histone H2AS1 Kinase Activity Regulation Of Response To Wounding Protein Kinase Inhibitor Activity Tissue Morphogenesis Catabolic Process Cytosol Cellular Response To Cytokine Stimulus Hormone Metabolic Process
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