ACAA1 and FEM1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACAA1	FEM1A
Description		acetyl-CoA acyltransferase 1	fem-1 homolog A
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Peroxisome Peroxisomal Matrix Cytosol Membrane Specific Granule Lumen	Ubiquitin Ligase Complex Cytoplasm Mitochondrion Cytosol Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-acyltransferase Activity Protein Binding Acetate CoA-transferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Acetyl-CoA C-myristoyltransferase Activity Long-chain Fatty Acyl-CoA Oxidase Activity	Protein Binding EP4 Subtype Prostaglandin E2 Receptor Binding Molecular Adaptor Activity Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Metabolic Process Phenylacetate Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process	MAPK Cascade Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Regulation Of Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways		alpha-linolenic acid (ALA) metabolism Beta-oxidation of very long chain fatty acids Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Neddylation
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756)	Height ( 31562340)
Interacting Genes		4 interacting genes: FEM1A HAT1 TFCP2 TXNDC11	11 interacting genes: ACAA1 GOLGA6L9 INCA1 KIFC3 MALT1 MYOM3 NDUFAB1 OGFOD1 PPM1F PTGER4 WWOX
Entrez ID		30	55527
HPRD ID		06815	16888
Ensembl ID		ENSG00000060971	ENSG00000141965
Uniprot IDs		A0A024R2M6 A0A140VJX0 P09110	Q9BSK4
PDB IDs		2IIK
Enriched GO Terms of Interacting Partners?		EP4 Subtype Prostaglandin E2 Receptor Binding
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