RHOD and ARHGAP29

Number of citations of the paper that reports this interaction (PMID 14749388)
16

Data Source:
BioGRID (two hybrid)

		RHOD	ARHGAP29
Gene Name		ras homolog family member D	Rho GTPase activating protein 29
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Cytosol Plasma Membrane	Cytosol
	Molecular Function	GTPase Activity GTP Binding Protein Kinase Binding	Rho GTPase Activator Activity PDZ Domain Binding Metal Ion Binding
	Biological Process	Protein Targeting Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Metabolic Process Lamellipodium Assembly Positive Regulation Of Cell Migration Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Focal Adhesion Assembly Regulation Of Actin Cytoskeleton Reorganization	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Signaling by Rho GTPases	Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		Height ( 20881960)	D-dimer levels ( 21502573)
Protein-Protein Interactions		14 interactors: ACVR1 ADCK5 ADRB2 ANKFY1 ARHGAP29 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1	7 interactors: AKT1 CDC42 KDM1A MAGEA11 PTPN13 RAP2A RHOD
Entrez ID		29984	9411
HPRD ID		05776	06674
Ensembl ID		ENSG00000173156
Uniprot IDs		E9PIG5 O00212	Q52LW3
PDB IDs		2J1L
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Organ Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta BMP Signaling Pathway Cell Development Pattern Specification Process Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Fate Commitment Activin Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Signaling Cell Surface Receptor Signaling Pathway Tissue Morphogenesis Negative Regulation Of Cell Proliferation Tissue Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Bone Mineralization Cell Morphogenesis Involved In Differentiation Positive Regulation Of Biomineral Tissue Development Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epithelial To Mesenchymal Transition Tube Morphogenesis Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Transcription, DNA-templated Mesenchyme Development Endocardial Cell Differentiation Branching Morphogenesis Of An Epithelial Tube Heart Morphogenesis In Utero Embryonic Development Morphogenesis Of An Epithelium Heart Development Endothelial Cell Activation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Stem Cell Development Regulation Of Bone Mineralization Positive Regulation Of Gene Expression Signal Transduction Germ Cell Development	Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Signaling Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Organelle Organization Cell Projection Assembly Muscle Cell Differentiation Positive Regulation Of Cell Adhesion Cell Projection Organization Blood Coagulation Hemostasis Endomembrane System Organization Actin Filament Bundle Assembly Cellular Protein Localization T Cell Costimulation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Projection Organization Gland Development Muscle Structure Development Adherens Junction Organization Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Glycogen Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Primitive Erythrocyte Differentiation Regulation Of Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Migration Wound Healing Actin Cytoskeleton Organization Regulation Of MAPK Cascade Small GTPase Mediated Signal Transduction Regulation Of Cell Adhesion Regulation Of Cell Motility Myeloid Leukocyte Differentiation Actin Filament-based Process Regulation Of Locomotion Regulation Of Cellular Component Movement Response To Wounding Positive Regulation Of Hair Follicle Cell Proliferation Intracellular Signal Transduction Positive Regulation Of Protein Phosphorylation Regulation Of Protein Binding Protein Localization Regulation Of Cellular Protein Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud ?		10nm 130nm 400nm 500ms 50nm 5x100hz bapta brevis buffering carbonylcyanide ctrl digitorum electrically electroporation fccp fdb flexor fluo footpads mag mfn2 mitofusin myoplasmic sarcomere tetani tetanic tethers transients trifluoromethoxyphenylhydrazone
Tagcloud (Difference) ?		10nm 130nm 400nm 500ms 50nm 5x100hz bapta brevis buffering carbonylcyanide ctrl digitorum electrically electroporation fccp fdb flexor fluo footpads mag mfn2 mitofusin myoplasmic sarcomere tetani tetanic tethers transients trifluoromethoxyphenylhydrazone
Tagcloud (Intersection) ?