SEC61A1 and ASNA1

Number of citations of the paper that reports this interaction (PMID 20676083)
55

Data Source:
BioGRID (pull down)

		SEC61A1	ASNA1
Gene Name		Sec61 alpha 1 subunit (S. cerevisiae)	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Rough Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Ribosome Binding	Transporter Activity ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent SRP-dependent Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Membrane Endoplasmic Reticulum Organization Cell Growth Response To Interferon-gamma Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Protein Targeting To ER	Transport Metabolic Process Inorganic Anion Transport Protein Insertion Into ER Membrane
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation ER-Phagosome pathway Adaptive Immune System
Drugs			Adenosine triphosphate
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ASNA1 BAG6 CALM1 HSPA5 MLH1 SERP1	13 interactors: APLN ASPH CACNA1A GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2
Entrez ID		29927	439
HPRD ID		15316	03555
Ensembl ID		ENSG00000058262	ENSG00000198356
Uniprot IDs		B3KME8 B3KNF6 P61619	O43681
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Insertion Into ER Membrane Response To Endoplasmic Reticulum Stress Protein Insertion Into Membrane Membrane Organization Substantia Nigra Development Endoplasmic Reticulum Organization Cellular Localization Synapsis Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Neural Nucleus Development Homologous Chromosome Segregation Positive Regulation Of Nuclease Activity Endomembrane System Organization Platelet Degranulation Positive Regulation Of Protein Kinase Activity Meiotic Chromosome Segregation Positive Regulation Of Kinase Activity Protein Localization To Organelle Midbrain Development Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Stress Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Transferase Activity Meiotic Spindle Midzone Assembly Regulation Of Protein Folding In Endoplasmic Reticulum Meiotic Metaphase I Plate Congression Cellular Response To Unfolded Protein Meiosis I ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Stress Catabolic Process Cell Activation Response To Unfolded Protein Negative Regulation Of Mitotic Recombination Cerebellum Structural Organization Positive Regulation Of Protein Phosphorylation Glucose Metabolic Process Regulation Of Protein Kinase Activity Protein Localization Regulation Of Cellular Protein Metabolic Process Brain Development Regulation Of Kinase Activity Meiotic Nuclear Division Head Development Cellular Macromolecule Catabolic Process System Development Positive Regulation Of Phosphorylation Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Metabolic Process	Protein Localization To Membrane Membrane Organization Transport Establishment Of Protein Localization To Membrane Calcium Ion-dependent Exocytosis Secretion Vesicle Fusion Cytoplasmic Transport Acid Secretion Cellular Protein Localization Cerebellar Molecular Layer Development Fetal Process Involved In Parturition Organelle Fusion Vestibular Nucleus Development Skeletal Muscle Cell Proliferation Peptidyl-aspartic Acid Hydroxylation Autocrine Signaling Intracellular Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Endomembrane System Organization Body Fluid Secretion Neurotransmitter Secretion Golgi Disassembly Cerebellum Maturation Eosinophil Degranulation Musculoskeletal Movement, Spinal Reflex Action Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cerebellum Development Protein Localization To Endoplasmic Reticulum Gamma-aminobutyric Acid Secretion Metencephalon Development Membrane Fusion Protein Localization Energy Reserve Metabolic Process Regulation Of Neurotransmitter Levels Thyroid Hormone Transport Regulation Of Acetylcholine Secretion, Neurotransmission Retrograde Protein Transport, ER To Cytosol Cell Growth Establishment Of Localization In Cell Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Exocytosis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Rhythmic Synaptic Transmission Response To Cortisol Thymidine Metabolic Process
Tagcloud ?			als14 als8 amyotrophic anchored anticipated belongs cofactors converts establishes faf1 fedax ffat hexamer homo immunoprecipitates interactors msp oligosaccharyl p97 phenylalanine proficient repertoire rpn2 trc uba ubiquitinated ubx vapa vapb
Tagcloud (Difference) ?			als14 als8 amyotrophic anchored anticipated belongs cofactors converts establishes faf1 fedax ffat hexamer homo immunoprecipitates interactors msp oligosaccharyl p97 phenylalanine proficient repertoire rpn2 trc uba ubiquitinated ubx vapa vapb
Tagcloud (Intersection) ?