OLA1 and ASCC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OLA1	ASCC2
Gene Name		Obg-like ATPase 1	activating signal cointegrator 1 complex subunit 2
Image
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Centrosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding GTP Binding ATPase Activity Ribosome Binding Ribosomal Large Subunit Binding Metal Ion Binding
	Biological Process		Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ASCC2 BARD1 BRCA1 HMGA1 PRMT5 TUBG1	38 interactors: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT JUN KDM1A LPL MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RELA RNF11 RPA1 RPLP1 SNRPB SNW1 SRF TBC1D17 TRIP4 URM1
Entrez ID		29789	84164
HPRD ID		15194	16515
Ensembl ID		ENSG00000138430	ENSG00000100325
Uniprot IDs		Q9NTK5	Q9H1I8
PDB IDs		2OHF	2DI0
Enriched GO Terms of Interacting Partners?		Protein K6-linked Ubiquitination Negative Regulation Of Gene Expression Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation DNA Repair Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Negative Regulation Of MRNA 3'-end Processing Oncogene-induced Cell Senescence Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Senescence-associated Heterochromatin Focus Assembly Protein Polyubiquitination Cellular Response To DNA Damage Stimulus Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Senescence Regulation Of Cell Cycle Regulation Of Gene Expression, Epigenetic Cellular Response To Indole-3-methanol Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Centriole Replication Cell Cycle Process DNA Metabolic Process Negative Regulation Of Protein Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Chromatin Silencing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Establishment Of Integrated Proviral Latency Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription DNA Replication Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Cellular Nitrogen Compound Metabolic Process Establishment Of Viral Latency Regulation Of Centriole Replication Histone H4-R3 Methylation Heterochromatin Assembly Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process Meiotic Spindle Organization	Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Myeloid Leukocyte Differentiation RNA Metabolic Process Nitrogen Compound Metabolic Process Myeloid Cell Differentiation Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation By Host Of Viral Transcription Leukocyte Differentiation RNA Biosynthetic Process Metabolic Process Response To Abiotic Stimulus Mitochondrion Organization Hemopoiesis Monocyte Differentiation Transcription, DNA-templated Telomere Maintenance Via Semi-conservative Replication Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Platelet Formation Protein Tetramerization Response To Radiation Platelet Morphogenesis Immune System Development Macromolecule Biosynthetic Process Telomere Maintenance Via Recombination Regulation Of Histone H3-K4 Methylation Nuclear DNA Replication Positive Regulation Of Transcription, DNA-templated Response To CAMP Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Response To Drug DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Response To Stress Gene Expression Blood Vessel Endothelial Cell Migration Interaction With Symbiont Learning Membrane Protein Proteolysis Aging Regulation Of Cell Proliferation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organophosphorus Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		1b acetate antioxidant biomarker comparative discovered dosing glatiramer highlighted ifnbeta ikbke insufficiency integrated knowledgebases mediators ms naive nd6 neuropathy nrf2 optic plausible pleiotropic preservation reduces relapsing remitting sclerosis signatures
Tagcloud (Difference) ?		1b acetate antioxidant biomarker comparative discovered dosing glatiramer highlighted ifnbeta ikbke insufficiency integrated knowledgebases mediators ms naive nd6 neuropathy nrf2 optic plausible pleiotropic preservation reduces relapsing remitting sclerosis signatures
Tagcloud (Intersection) ?