ABT1 and CDCA7L

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ABT1	CDCA7L
Description		activator of basal transcription 1	cell division cycle associated 7 like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Regulator Complex Nucleolus	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding	Protein Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spinal Cord Motor Neuron Differentiation Small-subunit Processome Assembly Positive Regulation Of DNA-templated Transcription	Regulation Of DNA-templated Transcription Positive Regulation Of Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Small cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Waist circumference variance ( 31453325) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Breast cancer ( 29059683) Gamma glutamyl transferase levels ( 33339817) Height ( 20189936) Multiple myeloma ( 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)
Interacting Genes		16 interacting genes: APP CCDC136 CDCA7L CEP70 DVL3 EMD FAM9B LZTS2 MAB21L3 PICK1 PPP1CC PRNP RNF151 SYNE4 TBP TSPYL2	68 interacting genes: ABT1 ANKRD1 ANKRD11 ANKRD23 AVPI1 AXIN1 BAG5 BEND7 BRPF1 BYSL CARD9 CAVIN1 CCDC116 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 DMAP1 EIF4A3 FAM217B FAM9B GOLGA2 GPRASP3 HSF2BP ING5 JADE2 KRTAP10-7 LMO1 MCRS1 MDFI MEOX2 MFAP1 MLH1 MORN3 MRPL28 MYC NDUFB7 NOL12 NOP2 PBX1 PBX2 PICK1 PIH1D1 PIP4K2B PPP1R16A PPP1R16B PRDM14 PRPF31 RRP7A SNRNP48 SSX1 SSX2IP STX11 SUV39H1 TADA2A TFPT TNNI1 TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF438 ZNF620 ZNF821
Entrez ID		29777	55536
HPRD ID		16469	11481
Ensembl ID		ENSG00000146109	ENSG00000164649
Uniprot IDs		Q9ULW3	A8K8X5 Q96GN5
PDB IDs			5YI9 6EMO
Enriched GO Terms of Interacting Partners?		Neuron Projection Organization Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Dendritic Spine Maintenance Intracellular Copper Ion Homeostasis Lamin Binding Regulation Of Protein Localization Copper Ion Homeostasis Cellular Response To Copper Ion Negative Regulation Of Canonical Wnt Signaling Pathway Molecular Function Activator Activity Positive Regulation Of Receptor Internalization Amyloid Fibril Formation Response To Copper Ion Negative Regulation Of Wnt Signaling Pathway Frizzled Binding Nuclear Outer Membrane Negative Regulation Of Fibroblast Proliferation Dendritic Spine Organization Negative Regulation Of Protein Localization To Nucleus Amyloid-beta Complex Growth Cone Lamellipodium Reproductive Process Regulation Of Response To Calcium Ion Regulation Of Synaptic Plasticity Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation TMEM240-body Male Gamete Generation Spermatogenesis Type 8 Metabotropic Glutamate Receptor Binding Postsynapse Organization Primary Ureteric Bud Growth Developmental Process Involved In Reproduction Cellular Response To Amyloid-beta Regulation Of Amyloid Precursor Protein Catabolic Process Postsynapse Regulation Of Establishment Of Protein Localization Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Receptor-mediated Endocytosis Cytoplasm Gamete Generation Regulation Of Canonical Wnt Signaling Pathway Response To Amyloid-beta Glial Cell Development Acetylcholine Receptor Activator Activity Positive Regulation Of Neuron Apoptotic Process Lipoprotein Particle	Nucleus RRNA Metabolic Process Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding RRNA Processing Regulation Of RNA Metabolic Process Histone Acetyltransferase Complex Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization RNA Metabolic Process Chromatin Remodeling Chromosome Nucleolus Nucleic Acid Metabolic Process RNA Processing Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Metabolic Process Regulation Of Primary Metabolic Process SnoRNA Localization Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Myosin Phosphatase Regulator Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Apoptotic Signaling Pathway MOZ/MORF Histone Acetyltransferase Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleolus Spliceosomal Complex Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Negative Regulation Of RNA Metabolic Process Skeletal System Morphogenesis DNA Binding Positive Regulation Of Biosynthetic Process Protein-RNA Complex Assembly Titin Binding Regulation Of DNA Replication Dorsal/ventral Axis Specification Regulation Of Signal Transduction By P53 Class Mediator Epigenetic Programming In The Zygotic Pronuclei Positive Regulation Of Telomere Maintenance In Response To DNA Damage
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