ABT1 and MAB21L3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ABT1	MAB21L3
Description		activator of basal transcription 1	mab-21 like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Regulator Complex Nucleolus
	Molecular Function	Nucleic Acid Binding DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding	Protein Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spinal Cord Motor Neuron Differentiation Small-subunit Processome Assembly Positive Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Small cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Waist circumference variance ( 31453325) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Coffee consumption ( 29367735) HDL cholesterol levels in HIV infection ( 33109212) Macular thickness ( 30535121)
Interacting Genes		16 interacting genes: APP CCDC136 CDCA7L CEP70 DVL3 EMD FAM9B LZTS2 MAB21L3 PICK1 PPP1CC PRNP RNF151 SYNE4 TBP TSPYL2	28 interacting genes: ABT1 AGGF1 ANKRD36B AP2M1 BEGAIN CT45A1 DVL3 EAF1 EHHADH EMD FAM9B FCHO1 GPATCH2L INO80E KRTAP10-9 KXD1 LBX1 LENG1 LZTS2 MED4 NTAQ1 PHC2 SPG21 SPRED1 STAC3 WHR1 ZCCHC10 ZNF165
Entrez ID		29777	126868
HPRD ID		16469	08245
Ensembl ID		ENSG00000146109	ENSG00000173212
Uniprot IDs		Q9ULW3	Q8N8X9
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Projection Organization Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Dendritic Spine Maintenance Intracellular Copper Ion Homeostasis Lamin Binding Regulation Of Protein Localization Copper Ion Homeostasis Cellular Response To Copper Ion Negative Regulation Of Canonical Wnt Signaling Pathway Molecular Function Activator Activity Positive Regulation Of Receptor Internalization Amyloid Fibril Formation Response To Copper Ion Negative Regulation Of Wnt Signaling Pathway Frizzled Binding Nuclear Outer Membrane Negative Regulation Of Fibroblast Proliferation Dendritic Spine Organization Negative Regulation Of Protein Localization To Nucleus Amyloid-beta Complex Growth Cone Lamellipodium Reproductive Process Regulation Of Response To Calcium Ion Regulation Of Synaptic Plasticity Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation TMEM240-body Male Gamete Generation Spermatogenesis Type 8 Metabotropic Glutamate Receptor Binding Postsynapse Organization Primary Ureteric Bud Growth Developmental Process Involved In Reproduction Cellular Response To Amyloid-beta Regulation Of Amyloid Precursor Protein Catabolic Process Postsynapse Regulation Of Establishment Of Protein Localization Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Receptor-mediated Endocytosis Cytoplasm Gamete Generation Regulation Of Canonical Wnt Signaling Pathway Response To Amyloid-beta Glial Cell Development Acetylcholine Receptor Activator Activity Positive Regulation Of Neuron Apoptotic Process Lipoprotein Particle
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