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GTF2F2 and MSX2
Number of citations of the paper that reports this interaction (PubMedID
9265625
)
0
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
GTF2F2
MSX2
Description
general transcription factor IIF subunit 2
msh homeobox 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor TFIIF Complex
Microtubule Cytoskeleton
RNA Polymerase II, Holoenzyme
RNA Polymerase II Transcription Regulator Complex
Chromatin
Nucleus
Transcription Regulator Complex
Cytosol
Nuclear Speck
Molecular Function
DNA Binding
Protein Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Transcription Cis-regulatory Region Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Transcription Elongation By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription By RNA Polymerase II
Ossification
Osteoblast Differentiation
Chondrocyte Development
Osteoblast Development
Outflow Tract Septum Morphogenesis
Outflow Tract Morphogenesis
Cardiac Conduction System Development
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Endochondral Bone Growth
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Population Proliferation
Animal Organ Morphogenesis
Anterior/posterior Pattern Specification
Signal Transduction Involved In Regulation Of Gene Expression
Embryonic Limb Morphogenesis
BMP Signaling Pathway
Positive Regulation Of BMP Signaling Pathway
Embryonic Forelimb Morphogenesis
Embryonic Hindlimb Morphogenesis
Wound Healing, Spreading Of Epidermal Cells
Embryonic Nail Plate Morphogenesis
Wound Healing
Odontogenesis
Embryonic Digit Morphogenesis
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Keratinocyte Differentiation
Positive Regulation Of Osteoblast Differentiation
Negative Regulation Of DNA-templated Transcription
Embryonic Morphogenesis
Stem Cell Differentiation
Cartilage Development
Positive Regulation Of Timing Of Catagen
Bone Trabecula Formation
Bone Morphogenesis
Cranial Suture Morphogenesis
Frontal Suture Morphogenesis
Branching Involved In Mammary Gland Duct Morphogenesis
Mammary Gland Epithelium Development
Cell Surface Receptor Signaling Pathway Involved In Heart Development
Enamel Mineralization
Cellular Response To Growth Factor Stimulus
Cellular Response To Estradiol Stimulus
Activation Of Meiosis
Mesenchymal Cell Apoptotic Process
Positive Regulation Of Mesenchymal Cell Apoptotic Process
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Regulation of RUNX2 expression and activity
Drugs
Diseases
Enlarged parietal foramina/cranium bifidum
Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
GWAS
Normal facial asymmetry (angle of surface orientation score) (
30631343
)
Type 2 diabetes (
25760438
)
Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) (
28090653
)
Alzheimer's disease (
33074286
)
Blond vs. brown/black hair color (
30531825
)
Chin dimples (
27182965
)
Chronotype (
30696823
)
Depressive symptoms (SSRI exposure interaction) (
25649181
)
Metabolite levels (
23823483
)
Night sleep phenotypes (
27126917
)
Red vs. brown/black hair color (
30531825
)
Resistant hypertension (
30237584
)
Stroke (
26089329
)
Interacting Genes
30 interacting genes:
AHR
AR
ARNT
ATF2
ATF4
CEBPA
CEBPG
CREB1
DYNLT2B
FHL2
FOS
GTF2B
GTF2E1
GTF2E2
GTF2F1
HMGA1
HTATSF1
JUN
KLF5
MAPRE3
MSX2
POLR2E
RPL27A
TAF5
TBP
TCEA1
TRAM2
URI1
YEATS4
ZMYND19
53 interacting genes:
ATXN1
CCDC102B
CEBPA
CLIC3
DLX2
DLX5
EPHB6
FBXW2
FOXH1
GATA2
GTF2F1
GTF2F2
HOXC9
LENG8
MAGED1
MAPK1
MAPK1IP1L
MGAT5B
MSX1
NAF1
NR3C1
PATZ1
PIAS2
PITX1
POLR3D
POU1F1
POU2AF1
POU2F2
POU6F2
PPARG
PRR13
RBPMS2
RHOXF2
RUNX2
SMAP2
SOX5
SPEN
TCF7L2
TENT5D
TLE1
TLE2
TLE5
TLX3
TOLLIP
TSSK3
VEZF1
XRCC5
XRCC6
YTHDF1
ZBTB17
ZC3H10
ZDHHC2
ZFHX3
Entrez ID
2963
4488
HPRD ID
01804
00421
Ensembl ID
ENSG00000188342
ENSG00000120149
Uniprot IDs
P13984
D6RIS4
P35548
PDB IDs
1BBY
1F3U
2BBY
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6O9L
7EDX
7EG7
7EG8
7EG9
7EGA
7EGB
7EGC
7ENA
7ENC
7LBM
7NVR
7NVS
7NVT
7NVU
7NVY
7NVZ
7NW0
7ZWD
7ZX7
7ZX8
8BVW
8BYQ
8BZ1
8GXQ
8GXS
8S51
8S52
8S54
8S55
8S5N
8WAK
8WAL
8WAN
8WAO
8WAP
8WAQ
8WAR
8WAS
8WAT
8WAU
8WAV
8WAW
8WAX
8WAY
8WAZ
8WB0
Enriched GO Terms of Interacting Partners
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DNA-templated Transcription
Transcription By RNA Polymerase II
RNA Polymerase II Transcription Regulator Complex
Nucleobase-containing Compound Biosynthetic Process
Transcription Factor TFIID Complex
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Nucleoplasm
Positive Regulation Of RNA Metabolic Process
RNA Metabolic Process
Transcription Regulator Complex
Macromolecule Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
DNA Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Regulation Of RNA Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
MRNA Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Chromatin
Positive Regulation Of Macromolecule Biosynthetic Process
Nucleic Acid Metabolic Process
Positive Regulation Of Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Transcription Cis-regulatory Region Binding
MRNA Transcription
Promoter-specific Chromatin Binding
DNA-templated Transcription Initiation
Sequence-specific Double-stranded DNA Binding
Integrated Stress Response Signaling
Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Macromolecule Metabolic Process
Nucleobase-containing Compound Metabolic Process
DNA-binding Transcription Factor Activity
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Nucleus
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Positive Regulation Of Metabolic Process
Regulation Of Gene Expression
RNA Polymerase II General Transcription Initiation Factor Binding
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of DNA-templated Transcription Initiation
Regulation Of Primary Metabolic Process
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Regulation Of DNA-templated Transcription Initiation
Regulation Of RNA Metabolic Process
DNA Binding
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Transcription Cis-regulatory Region Binding
Negative Regulation Of DNA-templated Transcription
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-binding Transcription Factor Activity
Chromatin
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Regulation Of Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Metabolic Process
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Nucleus
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Transcription Regulator Complex
Negative Regulation Of Biosynthetic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Embryonic Morphogenesis
DNA-templated Transcription
Sequence-specific Double-stranded DNA Binding
Nucleoplasm
Cell Fate Commitment
Positive Regulation Of Developmental Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Positive Regulation Of Cell Differentiation
Regulation Of Cell Differentiation
GABAergic Neuron Differentiation
Developmental Process
Transcription Factor TFIIF Complex
Protein-DNA Complex
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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