GSTM3 and CLVS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GSTM3	CLVS2
Description		glutathione S-transferase mu 3	clavesin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Sperm Fibrous Sheath Extracellular Exosome	Endosome Golgi Apparatus Trans-Golgi Network Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	Glutathione Transferase Activity Protein Binding Transferase Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Glutathione Binding	Protein Binding Lipid Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Glutathione Metabolic Process Establishment Of Blood-nerve Barrier Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Response To Estrogen Cellular Detoxification Of Nitrogen Compound	Lysosome Organization
Pathways		Glutathione conjugation	Lysosome Vesicle Biogenesis
Drugs		Glutathione Glutathione disulfide Deoxycholic acid
Diseases
GWAS		Alcohol dependence ( 33290381) Blood protein levels ( 30072576)	Refractive error ( 32231278) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		8 interacting genes: CLVS2 GSTM1 GSTM2 GSTM4 OGT SH3GL2 UCHL5 YWHAE	16 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2
Entrez ID		2947	134829
HPRD ID		00712	16666
Ensembl ID		ENSG00000134202	ENSG00000146352
Uniprot IDs		P21266 Q6FGJ9	Q5SYC1
PDB IDs		3GTU
Enriched GO Terms of Interacting Partners?		Nitrobenzene Metabolic Process Glutathione Binding Benzene-containing Compound Metabolic Process Xenobiotic Catabolic Process Glutathione Transferase Activity Long-chain Fatty Acid Biosynthetic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound Glutathione Metabolic Process Hepoxilin Biosynthetic Process Long-chain Fatty Acid Metabolic Process Xenobiotic Metabolic Process Fatty Acid Biosynthetic Process Calcium Channel Inhibitor Activity Enzyme Binding Modified Amino Acid Metabolic Process Catabolic Process Sulfur Compound Metabolic Process Carboxylic Acid Biosynthetic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Fatty Acid Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Lipid Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Identical Protein Binding Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Unsaturated Fatty Acid Metabolic Process Small Molecule Biosynthetic Process Regulation Of Heart Rate By Hormone Monocarboxylic Acid Metabolic Process Cellular Detoxification Lipid Biosynthetic Process Negative Regulation Of Blood-brain Barrier Permeability Negative Regulation Of Protein Catabolic Process Protein O-acetylglucosaminyltransferase Activity Cytosol Transmembrane Transporter Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Glutathione Derivative Biosynthetic Process Negative Regulation Of Proteolysis Regulation Of Calcium Ion Transmembrane Transport Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Leukotriene-C4 Synthase Activity Regulation Of Heart Rate By Chemical Signal Negative Regulation Of Calcium Ion Export Across Plasma Membrane Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Calcium Ion Export Across Plasma Membrane	Catalytic Activity Transition Metal Ion Binding Glutathione Transferase Activity Identical Protein Binding Cytosol Maleylacetoacetate Isomerase Activity Ethanolamine-phosphate Cytidylyltransferase Activity FMN Adenylyltransferase Activity FAD Biosynthetic Process FAD Diphosphatase Activity
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