CLVS2 and GSTZ1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLVS2	GSTZ1
Description		clavesin 2	glutathione S-transferase zeta 1
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding	Catalytic Activity Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Maleylacetoacetate Isomerase Activity Transferase Activity Isomerase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Lysosome Organization	L-phenylalanine Catabolic Process L-tyrosine Catabolic Process Glutathione Metabolic Process Aromatic Amino Acid Metabolic Process Cellular Oxidant Detoxification Cellular Detoxification
Pathways		Lysosome Vesicle Biogenesis	Glutathione conjugation Regulation of pyruvate dehydrogenase (PDH) complex Tyrosine catabolism
Drugs			Glutathione 1,4-Dithiothreitol Dichloroacetic acid Glycerin
Diseases
GWAS		Refractive error ( 32231278) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		16 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2	10 interacting genes: CLVS2 CRYAA GORASP2 GSS PLEKHG4 PPP1CC QARS1 TCP11 TRAF2 ZMYND12
Entrez ID		134829	2954
HPRD ID		16666	04785
Ensembl ID		ENSG00000146352	ENSG00000100577
Uniprot IDs		Q5SYC1	A0A0A0MR33 A0A0C4DFM0 G3V4T6 O43708
PDB IDs			1FW1 8E8P
Enriched GO Terms of Interacting Partners?		Catalytic Activity Transition Metal Ion Binding Glutathione Transferase Activity Identical Protein Binding Cytosol Maleylacetoacetate Isomerase Activity Ethanolamine-phosphate Cytidylyltransferase Activity FMN Adenylyltransferase Activity FAD Biosynthetic Process FAD Diphosphatase Activity
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