CLVS2 and PCYT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLVS2	PCYT2
Description		clavesin 2	phosphate cytidylyltransferase 2, ethanolamine
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane	Cytoplasm Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding	Catalytic Activity Ethanolamine-phosphate Cytidylyltransferase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity
	Biological Process	Lysosome Organization	Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phospholipid Biosynthetic Process Organophosphate Biosynthetic Process
Pathways		Lysosome Vesicle Biogenesis	Synthesis of PE
Drugs
Diseases
GWAS		Refractive error ( 32231278) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		16 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2	12 interacting genes: ADAMTS10 CLVS2 CRIP2 CRYAA DNMT3B GDF9 HOXA1 INCA1 KDM8 PSMA1 REL SETDB1
Entrez ID		134829	5833
HPRD ID		16666	04059
Ensembl ID		ENSG00000146352	ENSG00000185813
Uniprot IDs		Q5SYC1	B3KSC8 B7Z4W6 I3L1R7 Q99447
PDB IDs			3ELB 4XSV
Enriched GO Terms of Interacting Partners?		Catalytic Activity Transition Metal Ion Binding Glutathione Transferase Activity Identical Protein Binding Cytosol Maleylacetoacetate Isomerase Activity Ethanolamine-phosphate Cytidylyltransferase Activity FMN Adenylyltransferase Activity FAD Biosynthetic Process FAD Diphosphatase Activity
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