SAP30BP and THOC1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		SAP30BP	THOC1
Description		SAP30 binding protein	THO complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Protein Binding	DNA Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Response To Virus	MRNA Processing MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA Transport
Pathways		NoRC negatively regulates rRNA expression	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Rotator cuff tears ( 26350878)	Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)
Interacting Genes		25 interacting genes: DHX8 FHL2 FHL3 FRA10AC1 GOLGA2 GSK3B MLX OGT PRKAR1B PUF60 RBM17 RBM39 RPS6KA6 SAP30 SNCA SUPT5H TFIP11 THAP1 THOC1 U2AF2 USP7 WDR77 WDR83 ZNF212 ZNF408	32 interacting genes: AGR2 AKAP9 CTAG1A CTAG1B DHX8 ESS2 EXOC5 EXOSC7 FRA10AC1 GPRASP3 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C PRC1 PRPF6 RABGEF1 RB1 REL SAP30BP SF3B2 SNW1 TADA2A TFIP11 TRIM27 TRIM54 USHBP1 WDR77 ZMYND12
Entrez ID		29115	9984
HPRD ID		17094	09498
Ensembl ID		ENSG00000161526	ENSG00000079134
Uniprot IDs		Q9UHR5	Q96FV9
PDB IDs			1WXP 7APK 7ZNK 7ZNL
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing, Via Transesterification Reactions Nucleus MRNA Metabolic Process Nucleoplasm RNA Metabolic Process RNA Processing Spliceosomal Complex Regulation Of Nucleobase-containing Compound Metabolic Process TOR Signaling Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Catabolic Process Macromolecule Metabolic Process Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Nucleic Acid Binding Regulation Of RNA Splicing Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Catabolic Process Regulation Of Autophagy Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase A Catalytic Subunit Binding Catalytic Step 2 Spliceosome Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of Macromolecule Metabolic Process Sin3-type Complex Negative Regulation Of Autophagy Identical Protein Binding Negative Regulation Of Signal Transduction Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Stem Cell Population Maintenance Alternative MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Catalytic Step 2 Spliceosome Spliceosomal Complex RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing Cyclin/CDK Positive Transcription Elongation Factor Complex U2-type Precatalytic Spliceosome
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