DDOST and NXT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DDOST	NXT1
Description		dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	nuclear transport factor 2 like export factor 1
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Oligosaccharyltransferase Complex Membrane Azurophil Granule Membrane Intracellular Membrane-bounded Organelle Oligosaccharyltransferase Complex A Oligosaccharyltransferase Complex B	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Speck Nuclear RNA Export Factor Complex Nuclear Pore Central Transport Channel
	Molecular Function	Protein Binding Enzyme Activator Activity	Protein Binding Small GTPase Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Regulation Of Protein Stability Response To Cytokine T Cell Activation	RNA Export From Nucleus MRNA Export From Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus
Pathways		SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Neutrophil degranulation Advanced glycosylation endproduct receptor signaling Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane PD-L1(CD274) glycosylation and translocation to plasma membrane	Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS		Proportion of activated microglia (inferior temporal cortex) ( 30679421)	Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: ISG15 LTB4R2 MAPK6 NXT1 PTEN SRSF11 STING1	8 interacting genes: DDOST FBXO16 NXF1 NXF2 NXF3 RAN STAU1 XPO1
Entrez ID		1650	29107
HPRD ID		03728	16159
Ensembl ID		ENSG00000244038	ENSG00000132661
Uniprot IDs		P39656	Q9UKK6
PDB IDs		6S7O 6S7T 8B6L 8PN9	1JKG 1JN5 4WYK 6E5U
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Interferon-beta Production Septin Cytoskeleton Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Type I Interferon Production Regulation Of Interferon-beta Production Leukotriene B4 Receptor Activity Cyclic-di-GMP Binding STING Complex 2',3'-cyclic GMP-AMP Binding Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Regulation Of Type I Interferon Production Leukotriene Receptor Activity Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Protein Oligomerization Leukotriene Signaling Pathway	RNA Export From Nucleus Nuclear Export RNA Transport Nuclear RNA Export Factor Complex Nucleobase-containing Compound Transport MRNA Export From Nucleus Nuclear Transport Nucleocytoplasmic Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport Intracellular Transport Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Nuclear Export Signal Receptor Activity Cellular Localization RNA Binding Ribosomal Subunit Export From Nucleus Establishment Of Localization In Cell Protein Export From Nucleus Nuclear Envelope Nuclear Pore RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Stress Granule Cellular Response To Triglyceride Regulation Of Nucleocytoplasmic Transport Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex RNA Import Into Nucleus Positive Regulation By Virus Of Viral Protein Levels In Host Cell Response To Triglyceride Nucleic Acid Binding Regulation Of Intracellular Protein Transport LncRNA-mediated Post-transcriptional Gene Silencing Annulate Lamellae Cellular Response To Salt Protein Localization To Nucleus Oligosaccharyltransferase Complex B Germ Cell Development Oligosaccharyltransferase Complex A Pre-miRNA Binding Protein-containing Complex Importin-alpha Family Protein Binding Protein Domain Specific Binding Cellular Response To Mineralocorticoid Stimulus Protein Localization To Nucleolus Intracellular Protein Localization Anterograde Dendritic Transport Intracellular MRNA Localization Nuclear Inclusion Body
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?