PHPT1 and PPP1R16A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHPT1	PPP1R16A
Gene Name		phosphohistidine phosphatase 1	protein phosphatase 1, regulatory subunit 16A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Plasma Membrane
	Molecular Function	Phosphoprotein Phosphatase Activity Phosphohistidine Phosphatase Activity Calcium Channel Inhibitor Activity Ion Channel Binding	Protein Binding
	Biological Process	Protein Dephosphorylation Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Peptidyl-histidine Dephosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Lyase Activity Positive Regulation Of Cell Motility Regulation Of Actin Cytoskeleton Reorganization Negative Regulation Of ATP Citrate Synthase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ATXN1 ATXN1L DNMT3L PPP1R16A TINF2	20 interactors: AES CDH24 DDX27 FAM101B FSD1 HGS HLA-E IDO1 LY6H PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PUF60 RGMA TPP2 TRIP6 TXNRD1
Entrez ID		29085	84988
HPRD ID		17849	16454
Ensembl ID		ENSG00000054148	ENSG00000160972
Uniprot IDs		Q9NRX4 Q9P019	Q96I34
PDB IDs		2AI6 2HW4 2NMM 2OZW 2OZX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Biosynthetic Process Lung Alveolus Development Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein ADP-ribosylation Regulation Of Protein ADP-ribosylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Protein Glycosylation Lung Development Negative Regulation Of Gene Expression Respiratory Tube Development Respiratory System Development Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Regulation Of Hematopoietic Stem Cell Proliferation Telomere Assembly Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Protein Glycosylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Glycoprotein Metabolic Process DNA Methylation On Cytosine Nitrogen Compound Metabolic Process Regulation Of Telomere Maintenance Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Gene Expression By Genetic Imprinting Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Tube Development Telomere Maintenance Via Telomere Lengthening Genetic Imprinting Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of DNA Replication Regulation Of Metabolic Process DNA Methylation Visual Learning Positive Regulation Of Metabolic Process Gene Expression Visual Behavior DNA Metabolic Process Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Stem Cell Proliferation	Entrainment Of Circadian Clock By Photoperiod Triglyceride Catabolic Process Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Regulation Of Glycogen Catabolic Process Glycogen Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Dephosphorylation Regulation Of Circadian Rhythm Triglyceride Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Signaling Cell Division Circadian Rhythm Regulation Of Glycogen Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Dephosphorylation Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway Cellular Carbohydrate Metabolic Process Swimming Behavior Kynurenic Acid Biosynthetic Process Peptidyl-histidine Dephosphorylation Regulation Of Signal Transduction Lipid Catabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Energy Derivation By Oxidation Of Organic Compounds Rhythmic Process Regulation Of Signaling Adherens Junction Organization Negative Regulation Of ATP Citrate Synthase Activity Sulfate Assimilation Cytokine Production Involved In Inflammatory Response Protection From Natural Killer Cell Mediated Cytotoxicity Response To Light Stimulus Response To External Stimulus Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Tagcloud ?			acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Difference) ?			acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Intersection) ?