PHPT1

Description		phosphohistidine phosphatase 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Nuclear Body Leading Edge Of Lamellipodium Extracellular Exosome
	Molecular Function	Phosphoprotein Phosphatase Activity Enzyme Inhibitor Activity Protein Binding Hydrolase Activity Calcium Channel Inhibitor Activity Transmembrane Transporter Binding Actin Filament Binding Protein Histidine Phosphatase Activity
	Biological Process	Actin Cytoskeleton Organization Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of T Cell Receptor Signaling Pathway Lamellipodium Organization Positive Regulation Of Cell Motility
Pathways
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: ATXN1 ATXN1L CDC42 DNMT3L ERBB3 PPP1R16A TINF2 UBC
Entrez ID		29085
HPRD ID		17849
Ensembl ID		ENSG00000054148
Uniprot IDs		Q9NRX4 V9HWC4
PDB IDs		2AI6 2HW4 2NMM 2OZW 2OZX
Enriched GO Terms of Interacting Partners?		POZ Domain Binding Social Behavior Lung Alveolus Development Regulation Of Epithelial Cell Proliferation Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation GBD Domain Binding Storage Vacuole Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Perinucleolar Chromocenter Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Endothelin Receptor Signaling Pathway Involved In Heart Process Neuregulin Receptor Activity Memory Epigenetic Programing Of Female Pronucleus
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