PHPT1

Gene Name		phosphohistidine phosphatase 1
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Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Phosphoprotein Phosphatase Activity Phosphohistidine Phosphatase Activity Calcium Channel Inhibitor Activity Ion Channel Binding
	Biological Process	Protein Dephosphorylation Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Peptidyl-histidine Dephosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Lyase Activity Positive Regulation Of Cell Motility Regulation Of Actin Cytoskeleton Reorganization Negative Regulation Of ATP Citrate Synthase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: ATXN1 ATXN1L DNMT3L PPP1R16A TINF2
Entrez ID		29085
HPRD ID		17849
Ensembl ID		ENSG00000054148
Uniprot IDs		Q9NRX4 Q9P019
PDB IDs		2AI6 2HW4 2NMM 2OZW 2OZX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Biosynthetic Process Lung Alveolus Development Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein ADP-ribosylation Regulation Of Protein ADP-ribosylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Protein Glycosylation Lung Development Negative Regulation Of Gene Expression Respiratory Tube Development Respiratory System Development Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Regulation Of Hematopoietic Stem Cell Proliferation Telomere Assembly Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Protein Glycosylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Glycoprotein Metabolic Process DNA Methylation On Cytosine Nitrogen Compound Metabolic Process Regulation Of Telomere Maintenance Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Gene Expression By Genetic Imprinting Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Tube Development Telomere Maintenance Via Telomere Lengthening Genetic Imprinting Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of DNA Replication Regulation Of Metabolic Process DNA Methylation Visual Learning Positive Regulation Of Metabolic Process Gene Expression Visual Behavior DNA Metabolic Process Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Stem Cell Proliferation
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