GRIN2C and IL16

Number of citations of the paper that reports this interaction (PMID 10479680)
9

Data Source:
HPRD (two hybrid)

		GRIN2C	IL16
Gene Name		glutamate receptor, ionotropic, N-methyl D-aspartate 2C	interleukin 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Dendrite Postsynaptic Membrane	Extracellular Space Nucleus Cytoplasm Plasma Membrane
	Molecular Function	N-methyl-D-aspartate Selective Glutamate Receptor Activity Extracellular-glutamate-gated Ion Channel Activity Cation Channel Activity Protein Binding PDZ Domain Binding Protein N-terminus Binding	Cytokine Activity
	Biological Process	Transport Glutamate Receptor Signaling Pathway Synaptic Transmission Protein Localization Response To Wounding Directional Locomotion Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Negative Regulation Of Protein Catabolic Process Neuromuscular Process Controlling Balance Regulation Of Excitatory Postsynaptic Membrane Potential Cation Transmembrane Transport	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Immune Response Viral Process Leukocyte Chemotaxis Induction Of Positive Chemotaxis
Pathways		Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII CREB phosphorylation through the activation of Ras Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Unblocking of NMDA receptor, glutamate binding and activation Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs		L-Glutamic Acid Glycine Meperidine Tenocyclidine
Diseases
GWAS			Inattentive symptoms ( 18821565)
Protein-Protein Interactions		6 interactors: DLG3 DLG4 DLGAP1 ERBB2IP IL16 INADL	28 interactors: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ1 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A PPP1R12A PPP1R12B PPP1R12C SSSCA1 SUV39H1 USHBP1
Entrez ID		2905	3603
HPRD ID		00699	04329
Ensembl ID		ENSG00000161509	ENSG00000172349
Uniprot IDs		H0Y2V8 O15398 Q14957 Q8IW23	Q14005 Q9UME6
PDB IDs			1I16 1X6D
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Clustering Nucleotide Phosphorylation Synaptic Transmission Chemotaxis Basal Protein Localization Regulation Of Behavior Cell-cell Signaling Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Negative Regulation Of Receptor Internalization Locomotory Exploration Behavior Locomotion Dendritic Spine Morphogenesis Maintenance Of Cell Polarity Synaptic Vesicle Maturation Cellular Protein Localization Protein Localization To Membrane Vocalization Behavior Signaling Axon Guidance Cell Communication Induction Of Positive Chemotaxis Dendritic Spine Development Movement Of Cell Or Subcellular Component Establishment Of Planar Polarity Negative Regulation Of Receptor-mediated Endocytosis Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Morphogenesis Of A Polarized Epithelium Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Exploration Behavior Postsynaptic Membrane Organization Axonogenesis Cortical Cytoskeleton Organization Response To External Stimulus Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization Cellular Response To Stimulus Positive Regulation Of Positive Chemotaxis Nucleotide Metabolic Process Axon Development Positive Regulation Of Excitatory Postsynaptic Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation	Synaptic Transmission Potassium Ion Transmembrane Transport Potassium Ion Transport Potassium Ion Import Cell-cell Signaling Cation Transmembrane Transport Signaling Cell Communication Ion Transmembrane Transport Metal Ion Transport Regulation Of Ion Transmembrane Transport Cation Transport Transmembrane Transport Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Ion Transport Monovalent Inorganic Cation Transport Regulation Of Membrane Potential Regulation Of Cellular Process Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Sensory Perception Of Pain Startle Response Directional Locomotion Protein Homooligomerization Membrane Depolarization Negative Regulation Of Protein Catabolic Process Neuromuscular Process Regulation Of Resting Membrane Potential Regulation Of Neurological System Process Regulation Of Protein Catabolic Process Cell Cycle Regulation Of Excitatory Postsynaptic Membrane Potential Mitotic Cell Cycle Process Regulation Of Postsynaptic Membrane Potential Response To Wounding Protein Complex Assembly Cell Cycle Process Protein Oligomerization Negative Regulation Of Cell Cycle Potassium Ion Homeostasis Mitotic Cell Cycle Negative Regulation Of Chromosome Organization Locomotion G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Process Response To External Stimulus
Tagcloud ?		6j 6jxm atg autosomes backcross codon crosses dispersed egr epsilon espilon exons f1xc57bl flanking grinl interspecific mapping nucleas polyadenylation primer s1 spans spl spretus termination zeta
Tagcloud (Difference) ?		6j 6jxm atg autosomes backcross codon crosses dispersed egr epsilon espilon exons f1xc57bl flanking grinl interspecific mapping nucleas polyadenylation primer s1 spans spl spretus termination zeta
Tagcloud (Intersection) ?