GRIN2C

Gene Name		glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Dendrite Postsynaptic Membrane
	Molecular Function	N-methyl-D-aspartate Selective Glutamate Receptor Activity Extracellular-glutamate-gated Ion Channel Activity Cation Channel Activity Protein Binding PDZ Domain Binding Protein N-terminus Binding
	Biological Process	Transport Glutamate Receptor Signaling Pathway Synaptic Transmission Protein Localization Response To Wounding Directional Locomotion Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Negative Regulation Of Protein Catabolic Process Neuromuscular Process Controlling Balance Regulation Of Excitatory Postsynaptic Membrane Potential Cation Transmembrane Transport
Pathways		Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII CREB phosphorylation through the activation of Ras Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Unblocking of NMDA receptor, glutamate binding and activation Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs		L-Glutamic Acid Glycine Meperidine Tenocyclidine
Diseases
GWAS
Protein-protein Interactions		6 interactors: DLG3 DLG4 DLGAP1 ERBB2IP IL16 INADL
Entrez ID		2905
HPRD ID		00699
Ensembl ID		ENSG00000161509
Uniprot IDs		H0Y2V8 O15398 Q14957 Q8IW23
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Clustering Nucleotide Phosphorylation Synaptic Transmission Chemotaxis Basal Protein Localization Regulation Of Behavior Cell-cell Signaling Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Negative Regulation Of Receptor Internalization Locomotory Exploration Behavior Locomotion Dendritic Spine Morphogenesis Maintenance Of Cell Polarity Synaptic Vesicle Maturation Cellular Protein Localization Protein Localization To Membrane Vocalization Behavior Signaling Axon Guidance Cell Communication Induction Of Positive Chemotaxis Dendritic Spine Development Movement Of Cell Or Subcellular Component Establishment Of Planar Polarity Negative Regulation Of Receptor-mediated Endocytosis Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Morphogenesis Of A Polarized Epithelium Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Exploration Behavior Postsynaptic Membrane Organization Axonogenesis Cortical Cytoskeleton Organization Response To External Stimulus Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization Cellular Response To Stimulus Positive Regulation Of Positive Chemotaxis Nucleotide Metabolic Process Axon Development Positive Regulation Of Excitatory Postsynaptic Membrane Potential Cell Morphogenesis Involved In Neuron Differentiation
Tagcloud ?		6j 6jxm atg autosomes backcross codon crosses dispersed egr epsilon espilon exons f1xc57bl flanking grinl interspecific mapping nucleas polyadenylation primer s1 spans spl spretus termination zeta