GRIK5 and MLF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GRIK5	MLF1
Description		glutamate ionotropic receptor kainate type subunit 5	myeloid leukemia factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Plasma Membrane Membrane Kainate Selective Glutamate Receptor Complex Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Hippocampal Mossy Fiber To CA3 Synapse Postsynaptic Density Membrane	Nucleus Cytoplasm Cytoskeleton Cilium Ciliary Basal Body Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Glutamate-gated Receptor Activity Monoatomic Ion Channel Activity Ligand-gated Monoatomic Ion Channel Activity Kainate Selective Glutamate Receptor Activity Signaling Receptor Activity Ligand-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	DNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	Monoatomic Ion Transport Glutamate Receptor Signaling Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Monoatomic Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Membrane Potential Modulation Of Chemical Synaptic Transmission Excitatory Postsynaptic Potential Regulation Of Presynaptic Membrane Potential	Myeloid Progenitor Cell Differentiation DNA-templated Transcription Regulation Of DNA-templated Transcription Cell Differentiation Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle G1/S Phase Transition
Pathways		Activation of Ca-permeable Kainate Receptor
Drugs		Glutamic acid Butabarbital Topiramate
Diseases
GWAS		Bipolar disorder ( 21771265) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte count ( 32888494) Meat-related diet ( 32066663)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Major depressive disorder ( 27479909) PR interval ( 32439900) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 30224653)
Interacting Genes		9 interacting genes: DLG4 GOLM1 GPAA1 GRID2 GRIK1 GRIK2 GRIK3 LRSAM1 MLF1	9 interacting genes: CENPU COP1 COPS3 DNAJB6 GRIK5 MAGEA11 MEOX2 NRBP1 YWHAZ
Entrez ID		2901	4291
HPRD ID		02614	03239
Ensembl ID		ENSG00000105737	ENSG00000178053
Uniprot IDs		Q16478	A0A0S2Z4A4 A0A0S2Z4U8 A0A140VKD2 A0A494C175 A0A499FJ64 B2RD48 C9JNE5 C9K0D4 P58340 Q2TLE4
PDB IDs			3UAL 3UBW 6Y8E
Enriched GO Terms of Interacting Partners?		Ionotropic Glutamate Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway Glutamate Receptor Signaling Pathway Postsynaptic Density Membrane Kainate Selective Glutamate Receptor Complex Kainate Selective Glutamate Receptor Activity Ligand-gated Monoatomic Ion Channel Activity Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Synaptic Transmission, Glutamatergic Glutamate-gated Calcium Ion Channel Activity Glutamate-gated Receptor Activity Glutamate Receptor Activity Postsynaptic Membrane Regulation Of Postsynaptic Membrane Potential Chemical Synaptic Transmission Dendrite Cytoplasm Trans-synaptic Signaling Synaptic Signaling Monoatomic Ion Channel Activity Regulation Of Membrane Potential Ionotropic Glutamate Receptor Complex Modulation Of Chemical Synaptic Transmission Scaffold Protein Binding Cell-cell Signaling Regulation Of Synaptic Transmission, Glutamatergic Signaling Receptor Activity Signaling PDZ Domain Binding Negative Regulation Of Synaptic Transmission, Glutamatergic Cell Communication Ligand-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Presynaptic Membrane Synapse Calcium-mediated Signaling Regulation Of Long-term Neuronal Synaptic Plasticity AMPA Glutamate Receptor Complex Regulation Of Presynaptic Membrane Potential Glutamatergic Synapse Regulation Of Synaptic Plasticity Negative Regulation Of Synaptic Transmission Terminal Bouton Modulation Of Excitatory Postsynaptic Potential Receptor Clustering Monoatomic Ion Transmembrane Transport Regulation Of Neuronal Synaptic Plasticity Excitatory Postsynaptic Potential P2Y1 Nucleotide Receptor Binding Mossy Fiber Rosette Detection Of Cold Stimulus Involved In Thermoception Extracellularly Glutamate-gated Ion Channel Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?