MLF1 and NRBP1

Number of citations of the paper that reports this interaction (PMID 12176995)
6

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MLF1	NRBP1
Gene Name		myeloid leukemia factor 1	nuclear receptor binding protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm Cell Cortex Endomembrane System Membrane Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Protein Domain Specific Binding	Protein Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Cell Cycle Arrest	Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation ER To Golgi Vesicle-mediated Transport Gene Expression
Pathways			Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		6 interactors: CENPU COPS3 GRIK5 MAGEA11 NRBP1 YWHAZ	11 interactors: CDKN1A CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 TK1 TSC22D4
Entrez ID		4291	29959
HPRD ID		03239	05819
Ensembl ID		ENSG00000178053	ENSG00000115216
Uniprot IDs		B2RD48 P58340 Q2TLE4 Q5HYH4	Q9UHY1
PDB IDs		3UAL 3UBW
Enriched GO Terms of Interacting Partners?		Golgi Reassembly Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Histamine Secretion By Mast Cell Establishment Of Golgi Localization Golgi Inheritance Cullin Deneddylation Histamine Secretion Protein Retention In ER Lumen Protein Deneddylation Maintenance Of Protein Localization In Endoplasmic Reticulum Histamine Transport Golgi Localization Mast Cell Degranulation Protein Localization To Organelle Production Of Molecular Mediator Involved In Inflammatory Response Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Mast Cell Mediated Immunity Establishment Of Localization In Cell CENP-A Containing Nucleosome Assembly Lysosome Localization Positive Regulation Of Apoptotic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Programmed Cell Death Mast Cell Activation Positive Regulation Of Cell Death Histone Exchange Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis DNA Replication-independent Nucleosome Assembly Leukocyte Degranulation Cytoplasmic Transport Regulation Of Vesicle Fusion Regulation Of Synaptic Vesicle Transport Cellular Localization Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Regulated Secretory Pathway Chordate Embryonic Development Centromere Complex Assembly Embryo Development Ending In Birth Or Egg Hatching	Cell Cycle Cell Cycle Arrest Response To External Stimulus Response To Abiotic Stimulus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Tube Development Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Response To Organic Substance Regulation Of Kinase Activity Cellular Metabolic Process Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Cellular Response To Ionizing Radiation Glycogen Metabolic Process Positive Regulation Of Phosphorylation Cellular Response To Heat Positive Regulation Of Protein Modification Process Cellular Response To Mechanical Stimulus Response To Hormone Fetal Process Involved In Parturition Negative Regulation Of Phosphorylation Polysaccharide Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Reactive Oxygen Species Metabolic Process Cell Cycle Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Phosphorylation Signal Transduction In Response To DNA Damage Response To Radiation Negative Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Type B Pancreatic Cell Development Skeletal Muscle Cell Proliferation Superior Temporal Gyrus Development Heterocycle Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Aromatic Compound Metabolic Process Response To Heat Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Regulation Of Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Phosphatidylinositol-mediated Signaling Energy Reserve Metabolic Process Digestive Tract Development
Tagcloud ?		akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping hook3 integrative massively men1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl
Tagcloud (Difference) ?		akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping hook3 integrative massively men1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl
Tagcloud (Intersection) ?