DPH3 and PIH1D2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DPH3	PIH1D2
Gene Name		diphthamide biosynthesis 3	PIH1 domain containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	Ral GTPase Binding
	Biological Process	Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Protein Secretion Positive Regulation Of Binding
Pathways		Synthesis of diphthamide-EEF2 Post-translational protein modification Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ADIPOR1 PIH1D2 RPL8 SERGEF	11 interactors: DPH3 EIF4A2 GFAP IGF2BP3 ITGB3BP KRTAP12-4 MDFI MRFAP1L1 MVP RALA REL
Entrez ID		285381	120379
HPRD ID		16412	14021
Ensembl ID			ENSG00000150773
Uniprot IDs		Q96FX2	E9PD82 Q8WWB5
PDB IDs		2JR7
Enriched GO Terms of Interacting Partners?		Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Positive Regulation Of Ran GTPase Activity Cellular Response To Leptin Stimulus Response To Leptin	Negative Regulation Of RNA-directed RNA Polymerase Activity Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cytokine Biosynthetic Process MRNA Transport Negative Regulation Of Biosynthetic Process RNA Transport RNA Localization Membrane Raft Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Protein Transport Regulation Of Cellular Process Bergmann Glial Cell Differentiation Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Binding Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Protein Autophosphorylation Regulation Of Translation Signal Transduction Positive Regulation Of Glial Cell Proliferation Regulation Of Neurotransmitter Uptake Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Transferase Activity Regulation Of Cellular Localization Intermediate Filament Organization Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Protein Tyrosine Kinase Activity Trophoblast Giant Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Signaling Astrocyte Development Cell Communication Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification
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