DPH3 and ADIPOR1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DPH3	ADIPOR1
Description		diphthamide biosynthesis 3	adiponectin receptor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Plasma Membrane Membrane
	Molecular Function	Protein Binding Ferrous Iron Binding Iron Chaperone Activity Metal Ion Binding	Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity
	Biological Process	TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Protein Histidyl Modification To Diphthamide Negative Regulation Of Protein Secretion Positive Regulation Of Binding	Lipid Metabolic Process Fatty Acid Metabolic Process Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Glucose Homeostasis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways		Synthesis of diphthamide-EEF2	AMPK inhibits chREBP transcriptional activation activity
Drugs
Diseases
GWAS			Mean platelet volume ( 27863252 32888494)
Interacting Genes		6 interacting genes: ADIPOR1 MEOX2 PIH1D2 RPL8 SERGEF ZNF438	6 interacting genes: APPL1 DPH3 NAA20 NFKBIL1 STK11 TBXA2R
Entrez ID		285381	51094
HPRD ID		16412	06402
Ensembl ID		ENSG00000154813	ENSG00000159346
Uniprot IDs		Q96FX2	Q96A54
PDB IDs		2JR7	5LXG 6KRZ 6KS0
Enriched GO Terms of Interacting Partners?			Thromboxane Receptor Activity Thromboxane A2 Signaling Pathway Thromboxane A2 Receptor Activity Positive Regulation Of Macropinocytosis Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis N-terminal Peptidyl-glutamine Acetylation NatB Complex N-terminal Peptidyl-aspartic Acid Acetylation N-terminal Peptidyl-glutamic Acid Acetylation Intracellular Protein-containing Complex Protein N-terminal-methionine Acetyltransferase Activity TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Iron Chaperone Activity Protein Localization To Organelle Positive Regulation Of Vesicle Transport Along Microtubule Cellular Response To Lipopolysaccharide LRR Domain Binding Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Protein Localization To Nucleus Macropinosome Protein-N-terminal Amino-acid Acetyltransferase Activity
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