DPH3 and RPL8

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DPH3	RPL8
Gene Name		diphthamide biosynthesis 3	ribosomal protein L8
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	Protein Binding Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome RRNA Binding Poly(A) RNA Binding
	Biological Process	Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Protein Secretion Positive Regulation Of Binding	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Synthesis of diphthamide-EEF2 Post-translational protein modification Gamma carboxylation, hypusine formation and arylsulfatase activation	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ADIPOR1 PIH1D2 RPL8 SERGEF	12 interactors: ARIH2 ARL15 C11orf49 CHDH DPH3 DUSP23 FAM188A FGFR3 IL7R NUDT3 ST3GAL3 UPF2
Entrez ID		285381	6132
HPRD ID		16412	16044
Ensembl ID			ENSG00000161016
Uniprot IDs		Q96FX2	P62917
PDB IDs		2JR7	3J3B
Enriched GO Terms of Interacting Partners?		Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Positive Regulation Of Ran GTPase Activity Cellular Response To Leptin Stimulus Response To Leptin	Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Interleukin-7-mediated Signaling Pathway Glycine Betaine Biosynthetic Process From Choline Growth
Tagcloud ?			3a aldolase apex1 athanogene beclin1 bim bisphosphate calpain endosialin erb erythroblastic ezrin fms fructose hes1 hmgb1 hydroxysteroid metalloproteinases midkine minibrain mmps osteosarcoma polo proto recql4 shed sulfotransferase vegfa wwox
Tagcloud (Difference) ?			3a aldolase apex1 athanogene beclin1 bim bisphosphate calpain endosialin erb erythroblastic ezrin fms fructose hes1 hmgb1 hydroxysteroid metalloproteinases midkine minibrain mmps osteosarcoma polo proto recql4 shed sulfotransferase vegfa wwox
Tagcloud (Intersection) ?