CXCL17 and CCL8

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL17	CCL8
Description		C-X-C motif chemokine ligand 17	C-C motif chemokine ligand 8
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Protein Kinase Activity Cytokine Activity Protein Binding Chemokine Activity Heparin Binding Phospholipase Activator Activity CCR Chemokine Receptor Binding
	Biological Process	Angiogenesis Chemotaxis Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Cell Differentiation Macrophage Chemotaxis Negative Regulation Of Inflammatory Response Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Monocyte Chemotaxis	Positive Regulation Of Leukocyte Migration Calcium Ion Transport Intracellular Calcium Ion Homeostasis Exocytosis Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Response To Virus Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Host-mediated Suppression Of Viral Genome Replication Positive Regulation Of Myoblast Differentiation Eosinophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Negative Regulation Of Leukocyte Proliferation Positive Regulation Of Myoblast Fusion
Pathways
Drugs			Pidolic acid
Diseases
GWAS			Blood protein levels ( 30072576) Crohn's disease ( 22412388) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		16 interacting genes: CCL13 CCL2 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CCL8 CXCL10 CXCL12 CXCL14 CXCL9 PF4 XCL1 XCL2	20 interacting genes: ACKR1 ACKR2 ACKR4 CCL11 CCL13 CCL2 CCL26 CCR1 CCR3 CCR5 CXCL10 CXCL11 CXCL17 CXCL2 CXCL6 CXCL8 MMP3 PPBP VCAN XCL2
Entrez ID		284340	6355
HPRD ID		18264	03791
Ensembl ID		ENSG00000189377	ENSG00000108700
Uniprot IDs		Q6UXB2	P80075
PDB IDs			1ESR 7S59 7S5A
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Humoral Immune Response Chemotaxis Locomotion Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Granulocyte Migration Leukocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration Defense Response To Symbiont CCR Chemokine Receptor Binding Defense Response To Other Organism Cell Migration Cell Killing Cell Motility Response To Other Organism Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Response To External Biotic Stimulus Defense Response Extracellular Space Eosinophil Chemotaxis Eosinophil Migration Chemokine Receptor Binding Mononuclear Cell Migration Immune System Process Regulation Of Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Extracellular Region Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Lymphocyte Migration Positive Regulation Of Leukocyte Migration Positive Regulation Of T Cell Migration CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Lymphocyte Migration Response To Stress Positive Regulation Of Mononuclear Cell Migration	Cell Chemotaxis Chemokine-mediated Signaling Pathway Chemotaxis Locomotion Chemokine Activity Cell Migration Inflammatory Response Leukocyte Chemotaxis Cell Motility Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cytokine-mediated Signaling Pathway Leukocyte Migration Antimicrobial Humoral Response Immune Response Myeloid Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Cytokine Activity Defense Response Humoral Immune Response Immune System Process Granulocyte Chemotaxis Granulocyte Migration C-C Chemokine Binding Defense Response To Symbiont Defense Response To Other Organism Mononuclear Cell Migration Chemokine Receptor Activity C-C Chemokine Receptor Activity Extracellular Space Killing Of Cells Of Another Organism CCR Chemokine Receptor Binding Response To External Biotic Stimulus Response To Stress Response To Other Organism Cellular Response To Lipopolysaccharide CXCR Chemokine Receptor Binding Cell Killing Cellular Response To Molecule Of Bacterial Origin Response To Molecule Of Bacterial Origin Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Migration Extracellular Region Eosinophil Chemotaxis Eosinophil Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Positive Regulation Of Chemotaxis Calcium-mediated Signaling Response To Lipopolysaccharide Regulation Of Cell Migration
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