CXCL17 and CCL25

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL17	CCL25
Description		C-X-C motif chemokine ligand 17	C-C motif chemokine ligand 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Cytokine Activity Hormone Activity Protein Binding Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Angiogenesis Chemotaxis Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Cell Differentiation Macrophage Chemotaxis Negative Regulation Of Inflammatory Response Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Monocyte Chemotaxis	Positive Regulation Of Cell-matrix Adhesion Immune System Process Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Eosinophil Chemotaxis Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399)
Interacting Genes		16 interacting genes: CCL13 CCL2 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CCL8 CXCL10 CXCL12 CXCL14 CXCL9 PF4 XCL1 XCL2	11 interacting genes: ACKR2 ACKR4 CCL17 CCL5 CCR10 CCR9 CXCL11 CXCL12 CXCL17 PF4 PF4V1
Entrez ID		284340	6370
HPRD ID		18264	03976
Ensembl ID		ENSG00000189377	ENSG00000131142
Uniprot IDs		Q6UXB2	O15444
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Humoral Immune Response Chemotaxis Locomotion Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Granulocyte Migration Leukocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration Defense Response To Symbiont CCR Chemokine Receptor Binding Defense Response To Other Organism Cell Migration Cell Killing Cell Motility Response To Other Organism Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Response To External Biotic Stimulus Defense Response Extracellular Space Eosinophil Chemotaxis Eosinophil Migration Chemokine Receptor Binding Mononuclear Cell Migration Immune System Process Regulation Of Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Extracellular Region Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Lymphocyte Migration Positive Regulation Of Leukocyte Migration Positive Regulation Of T Cell Migration CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Lymphocyte Migration Response To Stress Positive Regulation Of Mononuclear Cell Migration	Cell Chemotaxis Chemotaxis Locomotion Chemokine-mediated Signaling Pathway Cell Migration Chemokine Activity Cell Motility Cytokine-mediated Signaling Pathway Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Immune Response Leukocyte Chemotaxis Immune System Process Antimicrobial Humoral Response Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Cytokine Activity Leukocyte Migration Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Humoral Immune Response CXCR Chemokine Receptor Binding Positive Regulation Of Monocyte Chemotaxis Defense Response Inflammatory Response Extracellular Space Killing Of Cells Of Another Organism Regulation Of Monocyte Chemotaxis Myeloid Leukocyte Migration External Side Of Plasma Membrane Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling CXCR3 Chemokine Receptor Binding Defense Response To Symbiont Defense Response To Other Organism Cell Killing Cell Surface Receptor Signaling Pathway Granulocyte Chemotaxis Chemokine Receptor Binding Granulocyte Migration Signal Transduction Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Transport Response To Other Organism T Cell Chemotaxis Macrophage Chemotaxis Positive Regulation Of Macrophage Chemotaxis G Protein-coupled Receptor Activity Macrophage Migration
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