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NEK8 and CSN2
Number of citations of the paper that reports this interaction (PMID
11864968
)
15
Data Source:
BioGRID
(enzymatic study)
NEK8
CSN2
Gene Name
NIMA-related kinase 8
casein beta
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Primary Cilium
Ciliary Inversin Compartment
Ciliary Base
Extracellular Region
Extracellular Space
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Enzyme Inhibitor Activity
Transporter Activity
Calcium Ion Binding
Biological Process
Mitotic Cell Cycle
Protein Phosphorylation
Microtubule-based Process
Organ Morphogenesis
Regulation Of Hippo Signaling
Calcium Ion Transport
Lactation
Negative Regulation Of Catalytic Activity
Pathways
Nuclear signaling by ERBB4
Signaling by ERBB4
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
ACVR1
CSN2
TCF4
TGFBR1
TRIM69
UBC
17 interactors:
AURKA
CDC42
CDK1
CELA1
CSN3
CSNK2A1
CSNK2B
FHL2
GRB2
HTRA2
NEK1
NEK2
NEK8
NFYC
PLK1
RAC1
TOLLIP
Entrez ID
284086
1447
HPRD ID
14822
00281
Ensembl ID
ENSG00000135222
Uniprot IDs
Q86SG6
P05814
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Pathway-restricted SMAD Protein Phosphorylation
Pharyngeal System Development
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Cellular Response To Growth Factor Stimulus
Response To Transforming Growth Factor Beta
Regulation Of Extrinsic Apoptotic Signaling Pathway
Activin Receptor Signaling Pathway
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Stem Cell Development
Negative Regulation Of Apoptotic Signaling Pathway
Signal Transduction By Phosphorylation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Cell Fate Commitment
Negative Regulation Of Cell Death
Stem Cell Differentiation
Embryonic Organ Morphogenesis
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Cell Cycle Process
Peptidyl-threonine Phosphorylation
Negative Regulation Of Signal Transduction
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Signaling
Glycogen Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Skeletal Muscle Tissue Development
Positive Regulation Of Signal Transduction
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Cell Cycle
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Cell Cycle
Positive Regulation Of Protein Kinase B Signaling
Embryonic Organ Development
Protein Metabolic Process
Gland Development
Polysaccharide Metabolic Process
Muscle Structure Development
Blood Vessel Development
Regulation Of Apoptotic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Vasculature Development
Positive Regulation Of Gene Expression
Regulation Of Cell Death
Cellular Protein Modification Process
Endocardial Cushion Cell Fate Commitment
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Anatomical Structure Development
Mitotic Cell Cycle
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Mitotic Nuclear Division
Developmental Process
Cell Projection Morphogenesis
Cell Part Morphogenesis
Mitotic Nuclear Division
Regulation Of Organelle Organization
Anatomical Structure Morphogenesis
Neuron Development
Neuron Projection Morphogenesis
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Axon Guidance
Mitotic Cell Cycle Process
Cell Morphogenesis
Regulation Of Mitotic Cell Cycle
Regulation Of Chromosome Segregation
Cell Division
Neuron Differentiation
Regulation Of Protein Metabolic Process
Cell Projection Organization
Centrosome Organization
Regulation Of Cell Division
Neuron Projection Development
Regulation Of Binding
Multicellular Organismal Development
Microtubule Organizing Center Organization
Positive Regulation Of Signal Transduction
Wnt Signaling Pathway
Cell Development
Axonogenesis
Protein Phosphorylation
G2/M Transition Of Mitotic Cell Cycle
Phosphorylation
Cell Cycle
Positive Regulation Of Protein Modification Process
Cellular Protein Catabolic Process
Regulation Of Cell Cycle
Axon Development
Regulation Of Metabolic Process
Mitotic Nuclear Envelope Disassembly
System Development
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Protein Stability
Chemotaxis
Tagcloud
?
0x
1x
25x
2x
4ebp1
4x
5x
8x
arg
arginine
bovine
casein
conditionally
csn1s
csn1s1
csn1s2
csn3
devoid
except
excess
experimental
gland
mammary
mtor
output
resemble
s6k
stat5
true
Tagcloud (Difference)
?
0x
1x
25x
2x
4ebp1
4x
5x
8x
arg
arginine
bovine
casein
conditionally
csn1s
csn1s1
csn1s2
csn3
devoid
except
excess
experimental
gland
mammary
mtor
output
resemble
s6k
stat5
true
Tagcloud (Intersection)
?