CSN2 and CSN3

Number of citations of the paper that reports this interaction (PubMedID 12146463)
0

Data Source:
HPRD (in vitro)

		CSN2	CSN3
Description		casein beta	casein kappa
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Enzyme Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process	Calcium Ion Transport Lactation	Lactation Protein Stabilization
Pathways		Nuclear signaling by ERBB4 Developmental Lineage of Mammary Gland Alveolar Cells	Miscellaneous transport and binding events
Drugs			Fostamatinib
Diseases
GWAS
Interacting Genes		18 interacting genes: AURKA CDC42 CDK1 CELA1 CSN3 CSNK2A1 CSNK2B FHL2 GRB2 HTRA2 NEK1 NEK2 NEK9 NFYC PLK1 RAC1 TOLLIP UBQLN2	10 interacting genes: CSN2 CSNK2A2 MAPRE1 MGAT5B PRNP RBPMS UBQLN1 UBQLN2 VENTX ZNF76
Entrez ID		1447	1448
HPRD ID		00281	03411
Ensembl ID		ENSG00000135222	ENSG00000171209
Uniprot IDs		P05814 W5RWE1	P07498
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Phosphorylation Centrosome Centrosome Separation Protein Kinase Activity Protein Phosphorylation Midbody Regulation Of Attachment Of Spindle Microtubules To Kinetochore Kinase Activity Regulation Of Proteasomal Protein Catabolic Process Protein Localization To Site Of Double-strand Break Spindle Midzone Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Cell Division Protein Kinase Binding Regulation Of Cell Cycle Regulation Of Mitotic Nuclear Division Wnt Signaling Pathway Organelle Organization Positive Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Mitotic Cell Cycle Spindle Microtubule Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Organelle Organization Mitotic Cell Cycle Regulation Of Nuclear Division Centrosome Cycle Signal Transduction In Response To DNA Damage Nucleotide Binding G2/M Transition Of Mitotic Cell Cycle G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Cell Cycle Cell Cycle G2/M Phase Transition Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Cytoskeleton Organization Ventricular Cardiac Muscle Cell Development Thioesterase Binding Regulation Of Cellular Component Organization Mitotic Nuclear Membrane Disassembly Cytoskeleton Cilium Disassembly Positive Regulation Of Protein Catabolic Process Cytosol Regulation Of Cell Cycle Process	Regulation Of Proteolysis Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Regulation Of Proteasomal Protein Catabolic Process Regulation Of Macroautophagy Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Molecular Condensate Scaffold Activity Type 8 Metabotropic Glutamate Receptor Binding Protein Localization To Astral Microtubule Negative Regulation Of Store-operated Calcium Channel Activity Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Regulation Of Protein Catabolic Process Regulation Of Autophagy Protein Localization To Mitotic Spindle Protein Localization To Spindle Microtubule Autophagosome Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Protein Kinase CK2 Complex Mitotic Spindle Astral Microtubule End Cortical Microtubule Cytoskeleton Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Identical Protein Binding Positive Regulation Of Proteasomal Protein Catabolic Process Type 5 Metabotropic Glutamate Receptor Binding MRNA CDS Binding Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Dendritic Spine Maintenance Cupric Ion Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Calcium Ion Transmembrane Transport
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