HID1 and RBBP8

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HID1	RBBP8
Gene Name		HID1 domain containing	retinoblastoma binding protein 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Trans Cisterna Cytoplasm Golgi Apparatus Golgi Medial Cisterna Cytoplasmic Microtubule Extracellular Vesicular Exosome Extrinsic Component Of Golgi Membrane	Nucleus Nucleoplasm Nucleolus Transcriptional Repressor Complex
	Molecular Function	Protein Binding	Single-stranded DNA Endodeoxyribonuclease Activity RNA Polymerase II Repressing Transcription Factor Binding RNA Polymerase II Transcription Corepressor Activity Damaged DNA Binding Protein Binding
	Biological Process	Intracellular Protein Transport Response To Brefeldin A	Cell Cycle Checkpoint G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic Blastocyst Hatching DNA Repair Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Nuclear Division DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing G2 DNA Damage Checkpoint Cell Division Meiotic Cell Cycle
Pathways			Meiotic recombination
Drugs
Diseases
GWAS			Height ( 18391951) Intracranial aneurysm ( 20364137) Tuberculosis ( 20694014)
Protein-Protein Interactions		7 interactors: BEGAIN CBS CSDE1 INPPL1 RAD51 RBBP8 RCN3	34 interactors: ATM BARD1 BRCA1 CLU CTBP1 CTBP2 EEF1A1 FXR2 FZR1 HID1 IGFBP7 IKBKG IKZF1 IKZF3 LIMS1 LMO1 LMO2 LMO4 MAP2K4 MRE11A PCNA PIN1 PRKDC PRRG4 RAF1 RB1 RBL1 RBL2 RGS17 SIAH1 SIAH2 TGIF2 TMEM54 WDYHV1
Entrez ID		283987	5932
HPRD ID		05766	04990
Ensembl ID		ENSG00000167861	ENSG00000101773
Uniprot IDs		Q8IV36	Q99708
PDB IDs			2L4Z
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cysteine Biosynthetic Process From Serine Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Transsulfuration Double-strand Break Repair Positive Regulation Of DNA Ligation Nuclear-transcribed MRNA Catabolic Process, No-go Decay DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Cysteine Biosynthetic Process L-cysteine Catabolic Process Cellular Response To Camptothecin Hydrogen Sulfide Biosynthetic Process Response To Camptothecin L-serine Catabolic Process Meiotic Cell Cycle DNA Recombinase Assembly Hydrogen Sulfide Metabolic Process DNA Recombination Cysteine Metabolic Process DNA Double-strand Break Processing Homocysteine Metabolic Process Blastocyst Hatching Regulation Of Double-strand Break Repair Via Homologous Recombination DNA Unwinding Involved In DNA Replication Sulfur Amino Acid Catabolic Process Serine Family Amino Acid Catabolic Process Ruffle Assembly Aromatic Compound Catabolic Process Cellular Modified Amino Acid Catabolic Process Sulfur Amino Acid Biosynthetic Process Cellular Metabolic Process Regulation Of Double-strand Break Repair Catabolic Process Mitotic Recombination L-serine Metabolic Process Phosphatidylinositol Dephosphorylation G2 DNA Damage Checkpoint DNA Catabolic Process, Exonucleolytic DNA Repair Ruffle Organization Phospholipid Dephosphorylation Cellular Response To Alkaloid Endochondral Ossification Sulfur Amino Acid Metabolic Process Reciprocal Meiotic Recombination Inositol Phosphate Metabolic Process	Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Cell Cycle Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Biosynthetic Process G2 DNA Damage Checkpoint Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Protein Metabolic Process Apoptotic Process Regulation Of Cell Death Cell Cycle Checkpoint Regulation Of Nucleic Acid-templated Transcription Programmed Cell Death Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Phosphorylation Cell Death Negative Regulation Of Gene Expression Death Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process DNA Damage Checkpoint Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Protein Modification Process Telomere Maintenance Regulation Of Phosphorus Metabolic Process Response To Organic Substance Immune System Process Heterocycle Metabolic Process Regulation Of Transcription, DNA-templated Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Cycle Process Positive Regulation Of Gene Expression Double-strand Break Repair Via Homologous Recombination Recombinational Repair
Tagcloud ?			advance breaks cluster ctip doi downregulates downregulating dsbs elusive faithful genotoxic hypersensitivity impairs mechanistic microrna mir october onc oncogenic oncomir online polycistronic publication recombination repressed resection strand suppresses untranslated
Tagcloud (Difference) ?			advance breaks cluster ctip doi downregulates downregulating dsbs elusive faithful genotoxic hypersensitivity impairs mechanistic microrna mir october onc oncogenic oncomir online polycistronic publication recombination repressed resection strand suppresses untranslated
Tagcloud (Intersection) ?