HID1 and CBS

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HID1	CBS
Gene Name		HID1 domain containing	cystathionine-beta-synthase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Trans Cisterna Cytoplasm Golgi Apparatus Golgi Medial Cisterna Cytoplasmic Microtubule Extracellular Vesicular Exosome Extrinsic Component Of Golgi Membrane	Nucleus Nucleolus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Cystathionine Beta-synthase Activity Protein Binding Enzyme Binding Heme Binding Pyridoxal Phosphate Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Modified Amino Acid Binding
	Biological Process	Intracellular Protein Transport Response To Brefeldin A	Sulfur Amino Acid Metabolic Process Cysteine Biosynthetic Process From Serine L-serine Metabolic Process L-serine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Transsulfuration L-cysteine Catabolic Process Cellular Nitrogen Compound Metabolic Process Homocysteine Catabolic Process Small Molecule Metabolic Process Homocysteine Metabolic Process Hydrogen Sulfide Biosynthetic Process
Pathways			Sulfur amino acid metabolism Metabolism of amino acids and derivatives Cysteine formation from homocysteine
Drugs			Pyridoxal Phosphate S-Adenosylmethionine L-Serine L-Cysteine Heme
Diseases
GWAS			Blood trace element (Se levels) ( 23720494) Homocysteine levels ( 20031578) Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: BEGAIN CBS CSDE1 INPPL1 RAD51 RBBP8 RCN3	20 interactors: CBX4 COL4A3BP DAXX EHHADH FXR2 HGS HID1 HTT PIAS1 PIAS3 PIN1 PRKAG1 PRKAR1A PSMA1 RANBP9 UBASH3A UBE2I UGP2 VTA1 ZDHHC17
Entrez ID		283987	875
HPRD ID		05766	01994
Ensembl ID		ENSG00000167861	ENSG00000160200
Uniprot IDs		Q8IV36	P35520 Q9NTF0
PDB IDs			1JBQ 1M54 4L0D 4L27 4L28 4L3V
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cysteine Biosynthetic Process From Serine Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Transsulfuration Double-strand Break Repair Positive Regulation Of DNA Ligation Nuclear-transcribed MRNA Catabolic Process, No-go Decay DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Cysteine Biosynthetic Process L-cysteine Catabolic Process Cellular Response To Camptothecin Hydrogen Sulfide Biosynthetic Process Response To Camptothecin L-serine Catabolic Process Meiotic Cell Cycle DNA Recombinase Assembly Hydrogen Sulfide Metabolic Process DNA Recombination Cysteine Metabolic Process DNA Double-strand Break Processing Homocysteine Metabolic Process Blastocyst Hatching Regulation Of Double-strand Break Repair Via Homologous Recombination DNA Unwinding Involved In DNA Replication Sulfur Amino Acid Catabolic Process Serine Family Amino Acid Catabolic Process Ruffle Assembly Aromatic Compound Catabolic Process Cellular Modified Amino Acid Catabolic Process Sulfur Amino Acid Biosynthetic Process Cellular Metabolic Process Regulation Of Double-strand Break Repair Catabolic Process Mitotic Recombination L-serine Metabolic Process Phosphatidylinositol Dephosphorylation G2 DNA Damage Checkpoint DNA Catabolic Process, Exonucleolytic DNA Repair Ruffle Organization Phospholipid Dephosphorylation Cellular Response To Alkaloid Endochondral Ossification Sulfur Amino Acid Metabolic Process Reciprocal Meiotic Recombination Inositol Phosphate Metabolic Process	Protein Sumoylation Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Protein Sumoylation Regulation Of Signaling Cell Cycle Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Sumoylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Androgen Receptor Signaling Pathway Regulation Of Protein Ubiquitination Endosomal Transport Endoplasmic Reticulum Organization Protein Transport Regulation Of Cell Cycle Peptidyl-amino Acid Modification Neural Plate Formation Response To Brefeldin A Positive Regulation Of SUMO Transferase Activity Establishment Of Protein Localization Viral Process Monocarboxylic Acid Metabolic Process Intracellular Transport Response To Stimulus Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Cell Cycle Process Negative Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity ER To Golgi Ceramide Transport Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Ligase Activity Small Molecule Metabolic Process Mitotic Cell Cycle Process Mesoderm Formation Regulation Of Catalytic Activity Negative Regulation Of Signaling Mesoderm Morphogenesis Organelle Organization Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?			catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose
Tagcloud (Difference) ?			catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose
Tagcloud (Intersection) ?