TTC9C and TADA2A

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		TTC9C	TADA2A
Name		tetratricopeptide repeat domain 9C	transcriptional adaptor 2A
Structure		No pdb structure
GO Annotations	Cellular Component	None	SAGA Complex Nucleus Nucleoplasm Chromosome SAGA-type Complex Mitotic Spindle ATAC Complex
	Molecular Function	Protein Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	None	Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle
Pathways		None	HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )	Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334 ) Monocyte percentage of white cells ( 32888494 ) Ovarian cancer ( 23535730 ) Plateletcrit ( 32888494 ) White blood cell count ( 32888494 )
Interacting Genes		17 interacting genes: CDYL CEBPA GOLGA2 HSF2BP KRT31 KRT34 KRT40 LZTS1 MEOX2 NICN1 PLEKHF2 PNMA1 SKP1 TADA2A TOLLIP TRIM54 USHBP1	49 interacting genes: AIRIM ARNT2 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NFE2L2 NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688
Entrez ID		283237	6871
HPRD ID		14530	03784
Ensembl ID		ENSG00000162222	ENSG00000276234
Uniprot IDs		Q8N5M4	A0A024R0Y4 A0A087WWR4 A0A0S2Z4G1 B3KU13 O75478
PDB IDs		Not available	1X41
GO Terms Enriched among Interactors		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Epithelial Cell Differentiation	Protein Binding U2-type Precatalytic Spliceosome Nuclear Speck Exon-exon Junction Subcomplex Mago-y14 Nucleus U2-type Spliceosomal Complex Spliceosomal Complex MRNA Splicing, Via Spliceosome MRNA Processing Negative Regulation Of Stress-activated MAPK Cascade Membrane Fission RNA Splicing, Via Transesterification Reactions Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Cytoplasm Centrosome Nuclear Export RNA Splicing ATAC Complex Nuclear Transport Nucleocytoplasmic Transport Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay