BLOC1S4 and BLOC1S6

Number of citations of the paper that reports this interaction (PMID 15102850)
57

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BLOC1S4	BLOC1S6
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol BLOC-1 Complex	Nucleoplasm Cytoplasm Endosome Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex
	Molecular Function	Protein Binding	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Neuromuscular Process Controlling Balance Membrane Organization Platelet Aggregation	Post-Golgi Vesicle-mediated Transport Blood Coagulation Anterograde Axon Cargo Transport Synaptic Vesicle Docking Melanocyte Differentiation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation Membrane Organization Membrane Fusion
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AIMP2 BLOC1S1 BLOC1S2 BLOC1S5 BLOC1S6 EPB42 SNAPIN	38 interactors: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 CCDC136 CCDC22 CCDC53 CCHCR1 CDK5R1 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 KRT13 LURAP1 MED21 NDC80 NDN NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 SKA1 SLC4A1 SMN2 SNAPIN STX11 STX12 SYCE3 TPM3 WDYHV1
Entrez ID		55330	26258
HPRD ID		12035	16055
Ensembl ID		ENSG00000186222	ENSG00000104164
Uniprot IDs		Q9NUP1	B3KY40 Q9UL45
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Axon Cargo Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Synaptic Transmission Microtubule-based Process Neuron Projection Development Cell Differentiation Cell Development Cell-cell Signaling Neuron Development Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Platelet Dense Granule Organization Neuron Differentiation Positive Regulation Of Pigment Cell Differentiation Cell Projection Organization System Development Positive Regulation Of Developmental Pigmentation Multicellular Organismal Development Vesicle-mediated Transport Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Developmental Pigmentation Intracellular Transport Endosomal Transport Generation Of Neurons Neurogenesis Developmental Process Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Membrane Organization Secretory Granule Organization Melanosome Localization Establishment Of Localization In Cell Synaptic Vesicle Exocytosis	Anterograde Synaptic Vesicle Transport Establishment Of Localization In Cell Axon Cargo Transport Melanosome Organization Pigment Granule Organization Organelle Organization Cellular Pigmentation Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Organelle Localization Synaptic Vesicle Transport Movement Of Cell Or Subcellular Component Establishment Of Vesicle Localization Intracellular Transport Pigmentation Vesicle Organization Establishment Of Organelle Localization Vesicle Localization Membrane Organization Neuron Development Microtubule-based Process Neuron Projection Development Platelet Dense Granule Organization Microtubule-based Movement Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Vesicle-mediated Transport Protein Localization Protein Transport Establishment Of Protein Localization Cell Development Post-Golgi Vesicle-mediated Transport Generation Of Neurons Cellular Protein Localization Neurogenesis Neuron Recognition Secretory Granule Organization Transport Endomembrane System Organization Golgi Vesicle Transport Vesicle Fusion Nervous System Development Mitotic Nuclear Division Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Exocytosis Organelle Fusion
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