GP1BA and GP9

Number of citations of the paper that reports this interaction (PMID 2436691)
15

Data Source:
HPRD (in vivo)

		GP1BA	GP9
Gene Name		glycoprotein Ib (platelet), alpha polypeptide	glycoprotein IX (platelet)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Anchored Component Of External Side Of Plasma Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Thrombin Receptor Activity
	Biological Process	Cell Morphogenesis Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation Regulation Of Blood Coagulation Fibrinolysis Thrombin Receptor Signaling Pathway	Cell Adhesion Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation
Pathways			Platelet Adhesion to exposed collagen Intrinsic Pathway GP1b-IX-V activation signalling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Formation of Fibrin Clot (Clotting Cascade)
Drugs		Alpha-D-Mannose	Quinine
Diseases
GWAS		Platelet counts ( 22139419 20139978)
Protein-Protein Interactions		16 interactors: CTSG DDIT3 F11 F12 F2 FLNA FLNB GP5 GP9 ITGAM KNG1 OSGEP SELP TPST1 VWF YWHAZ	5 interactors: APPBP2 GP1BA GP1BB HOXA1 SPRY2
Entrez ID		2811	2815
HPRD ID		01976	01432
Ensembl ID		ENSG00000185245	ENSG00000169704
Uniprot IDs		E7ES66	P14770
PDB IDs			3REZ
Enriched GO Terms of Interacting Partners?		Blood Coagulation, Intrinsic Pathway Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Platelet Activation Protein Activation Cascade Regulation Of Blood Coagulation Cell Activation Response To Stress Regulation Of Wound Healing Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Inflammatory Response Regulation Of Fibrinolysis Platelet Degranulation Defense Response Regulation Of Platelet Activation Positive Regulation Of Blood Coagulation Response To Stimulus Exocytosis Positive Regulation Of Fibrinolysis Positive Regulation Of Coagulation Positive Regulation Of Wound Healing Secretion By Cell MRNA Transcription From RNA Polymerase II Promoter MRNA Transcription Secretion Negative Regulation Of Platelet Activation Cell Adhesion Regulation Of Ion Homeostasis Cellular Extravasation Fibrinolysis Cytosolic Calcium Ion Homeostasis Leukocyte Migration Positive Regulation Of Intracellular Transport Protein Processing Cellular Localization Negative Regulation Of Determination Of Dorsal Identity Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Protein Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Acute Inflammatory Response Positive Regulation Of Transport Establishment Of Localization In Cell Threonylcarbamoyladenosine Biosynthetic Process See more	Blood Coagulation, Intrinsic Pathway Inner Ear Morphogenesis Optokinetic Behavior Abducens Nerve Formation Ear Morphogenesis Facial Nucleus Development Sensory Perception Of Sound Protein Activation Cascade Sensory Perception Of Mechanical Stimulus Rhombomere 4 Development Semicircular Canal Formation Inner Ear Development Platelet Activation Rhombomere 3 Development Rhombomere 5 Development Ear Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Lung Growth Embryonic Neurocranium Morphogenesis Embryonic Organ Morphogenesis Regulation Of Neurotrophin TRK Receptor Signaling Pathway Outer Ear Morphogenesis Semicircular Canal Morphogenesis Rhombomere Development Thrombin Receptor Signaling Pathway Facial Nerve Structural Organization Pons Development Facial Nerve Morphogenesis Bud Elongation Involved In Lung Branching Semicircular Canal Development Blood Coagulation Hemostasis Tube Morphogenesis Negative Regulation Of Peptidyl-threonine Phosphorylation Parasympathetic Nervous System Development Embryonic Organ Development Negative Regulation Of Ras GTPase Activity Anatomical Structure Arrangement Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Cochlea Morphogenesis Branch Elongation Of An Epithelium Regulation Of Body Fluid Levels Sensory Organ Development Wound Healing Fibrinolysis Embryonic Morphogenesis Motor Neuron Axon Guidance Negative Regulation Of GTPase Activity Axis Elongation Cell Activation See more
Tagcloud ?		acantholysis anxa8l1 atp2c1 blistering c5a cd1b cd32 cd88 cdh8 cdh9 chrm3 chrnd chrne col21a1 cyb5b desmoglein dra dsc1 dsc3 justifies mucocutaneous multiplexed ndufs1 pdha1 pemphigus pkp3 pmp22 slc36a4 sod2
Tagcloud (Difference) ?		acantholysis anxa8l1 atp2c1 blistering c5a cd1b cd32 cd88 cdh8 cdh9 chrm3 chrnd chrne col21a1 cyb5b desmoglein dra dsc1 dsc3 justifies mucocutaneous multiplexed ndufs1 pdha1 pemphigus pkp3 pmp22 slc36a4 sod2
Tagcloud (Intersection) ?