GP9 and GP1BB

Number of citations of the paper that reports this interaction (PMID 12036872)
6

Data Source:
HPRD (in vivo)

		GP9	GP1BB
Gene Name		glycoprotein IX (platelet)	glycoprotein Ib (platelet), beta polypeptide
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function		Transmembrane Signaling Receptor Activity Protein Binding
	Biological Process	Cell Adhesion Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation	Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation
Pathways		Platelet Adhesion to exposed collagen Intrinsic Pathway GP1b-IX-V activation signalling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Formation of Fibrin Clot (Clotting Cascade)	Platelet Adhesion to exposed collagen Intrinsic Pathway GP1b-IX-V activation signalling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Formation of Fibrin Clot (Clotting Cascade)
Drugs		Quinine
Diseases
GWAS			DNA methylation (parent-of-origin) ( 23725790)
Protein-Protein Interactions		5 interactors: APPBP2 GP1BA GP1BB HOXA1 SPRY2	4 interactors: GP9 PRKACA TGFB1I1 YWHAZ
Entrez ID		2815	2812
HPRD ID		01432	00729
Ensembl ID		ENSG00000169704
Uniprot IDs		P14770	P13224
PDB IDs		3REZ	3REZ 3RFE
Enriched GO Terms of Interacting Partners?		Blood Coagulation, Intrinsic Pathway Inner Ear Morphogenesis Optokinetic Behavior Abducens Nerve Formation Ear Morphogenesis Facial Nucleus Development Sensory Perception Of Sound Protein Activation Cascade Sensory Perception Of Mechanical Stimulus Rhombomere 4 Development Semicircular Canal Formation Inner Ear Development Platelet Activation Rhombomere 3 Development Rhombomere 5 Development Ear Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Lung Growth Embryonic Neurocranium Morphogenesis Embryonic Organ Morphogenesis Regulation Of Neurotrophin TRK Receptor Signaling Pathway Outer Ear Morphogenesis Semicircular Canal Morphogenesis Rhombomere Development Thrombin Receptor Signaling Pathway Facial Nerve Structural Organization Pons Development Facial Nerve Morphogenesis Bud Elongation Involved In Lung Branching Semicircular Canal Development Blood Coagulation Hemostasis Tube Morphogenesis Negative Regulation Of Peptidyl-threonine Phosphorylation Parasympathetic Nervous System Development Embryonic Organ Development Negative Regulation Of Ras GTPase Activity Anatomical Structure Arrangement Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Cochlea Morphogenesis Branch Elongation Of An Epithelium Regulation Of Body Fluid Levels Sensory Organ Development Wound Healing Fibrinolysis Embryonic Morphogenesis Motor Neuron Axon Guidance Negative Regulation Of GTPase Activity Axis Elongation Cell Activation	Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Positive Regulation Of Dense Core Granule Biogenesis Morphogenesis Of Embryonic Epithelium Histone H3-T6 Phosphorylation Intrinsic Apoptotic Signaling Pathway Response To Stress Cell Adhesion Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Transport Golgi Reassembly Histamine Secretion By Mast Cell Ubiquitin-dependent SMAD Protein Catabolic Process Peptidyl-serine Autophosphorylation Establishment Of Golgi Localization Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Golgi Inheritance Apoptotic Signaling Pathway Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Histamine Secretion Regulation Of Tight Junction Assembly Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Histamine Transport Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Intracellular Transport Endomembrane System Organization Regulation Of Cellular Component Organization Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Response To Parathyroid Hormone Positive Regulation Of Protein Export From Nucleus Cell Communication By Electrical Coupling Golgi Localization Activation Of Protein Kinase A Activity Blood Coagulation, Intrinsic Pathway Morphogenesis Of An Epithelium Negative Regulation Of Glucose Transport Cellular Response To Epinephrine Stimulus Regulation Of Platelet Aggregation Sperm Capacitation Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
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